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Articles Published Processes
1/21/2022 8:16:14 AM | Browse: 391 | Download: 838
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Received |
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2021-10-08 20:23 |
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Peer-Review Started |
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2021-10-08 20:24 |
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To Make the First Decision |
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Return for Revision |
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2021-11-17 08:03 |
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Revised |
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2021-11-23 19:59 |
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Second Decision |
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2021-12-29 03:10 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-12-31 22:22 |
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Articles in Press |
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2021-12-31 22:22 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-01-18 04:30 |
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Publish the Manuscript Online |
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2022-01-21 08:16 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Case Report |
| Article Title |
Acute liver failure secondary to acute antibody mediated rejection after compatible liver transplant: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Todd J Robinson, James B Hendele, Idoia Gimferrer, Nicolae Leca, Scott W Biggins, Jorge D Reyes and Lena Sibulesky |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Lena Sibulesky, MD, Associate Professor, Surgeon, Department of Surgery, University of Washington Medical Center, UWMC 1959 NE Pacific St, Box 356410 Seattle, Seattle, WA 98195, United States. lenasi@uw.edu |
| Key Words |
Liver transplant; Acute antibody mediated rejection; Acute liver failure; Donor specific antibody; Liver rejection; Case report |
| Core Tip |
The liver has traditionally been regarded as resistant to antibody-mediated rejection (AMR). AMR in liver transplants is a field in its infancy compared to kidney and lung transplants. We present a case of a 56 year-old woman with alpha-1-antitrypsin disease who underwent ABO compatible liver transplant. The flow cytometric crossmatches were noted to be positive for T and B lymphocytes. After initial posttransplant recovery she progressively developed acute liver failure with evidence of antibody mediated rejection with portal inflammation, bile duct injury, endothelitis, and extensive centrizonal necrosis, and C4d staining on allograft biopsy and elevated donor-specific antibodies. Despite various interventions including plasmapheresis and immunomodulating therapy, she required retranpslantation. |
| Publish Date |
2022-01-21 08:16 |
| Citation |
Robinson TJ, Hendele JB, Gimferrer I, Leca N, Biggins SW, Reyes JD, Sibulesky L. Acute liver failure secondary to acute antibody mediated rejection after compatible liver transplant: A case report. World J Hepatol 2022; 14(1): 287-294 |
| URL |
https://www.wjgnet.com/1948-5182/full/v14/i1/287.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v14.i1.287 |
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