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Articles Published Processes
8/26/2014 3:51:00 PM | Browse: 1081 | Download: 1267
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Received |
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2013-11-09 10:57 |
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Peer-Review Started |
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2013-11-09 19:36 |
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To Make the First Decision |
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2013-12-26 11:25 |
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Return for Revision |
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2014-01-06 16:21 |
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Revised |
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Second Decision |
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2014-03-19 13:50 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-03-19 15:20 |
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Articles in Press |
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2014-05-23 09:19 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2014-04-16 10:15 |
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Typeset the Manuscript |
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2014-05-29 13:06 |
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Publish the Manuscript Online |
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2014-06-16 16:19 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Clinical Trials Study |
Article Title |
Should peri-gastrectomy gastric acidity be our focus among gastric cancer patients?
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Manuscript Source |
Invited Manuscript |
All Author List |
Lei Huang, A-Man Xu, Tuan-Jie Li, Wen-Xiu Han and Jing Xu |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China |
81172036 |
Foundation of Anhui Science and Technology Agency |
12070403061 |
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Corresponding Author |
A-Man Xu, MD, Professor, Chief Physician, Department of General Surgery, the First Affiliated Hospital of Anhui Medical University, No. 218, Jixi Road, Hefei 230022, Anhui Province, China. hlzt1991@sina.com |
Key Words |
Gastric carcinoma; Gastrectomy; Reflux; Acidity; Gastrointestinal juice |
Core Tip |
Necessity of peri-gastrectomy acid suppression for gastric cancer patients remains controversial. This innovative prospective study showed: before surgery, gastric pH was higher than the threshold of hypoacidity, and affected by age, tumor size and differentiation grade, and potassium and bicarbonate ions; advanced malignancies were accompanied with higher pH; after operation, gastric pH in all groups was of weak-acidity and higher than that pre-gastrectomy; six months later, gastric pH was comparable to that on days 3-5; reflux symptom was significantly associated with patient’s body mass index, direct and indirect bilirubin, and total bile acid, while pH played no role. |
Publish Date |
2014-06-16 16:19 |
Citation |
Huang L, Xu AM, Li TJ, Han WX, Xu J. Should peri-gastrectomy gastric acidity be our focus among gastric cancer patients? World J Gastroenterol 2014; 20(22): 6981-6988 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i22/6981.htm |
DOI |
10.3748/wjg.v20.i22.6981 |
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