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Articles Published Processes
6/2/2022 10:05:36 AM | Browse: 361 | Download: 1040
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Received |
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2021-10-10 02:18 |
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Peer-Review Started |
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2021-10-10 02:19 |
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To Make the First Decision |
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Return for Revision |
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2022-01-13 00:23 |
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Revised |
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2022-01-21 13:47 |
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Second Decision |
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2022-04-12 02:04 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-04-21 17:42 |
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Articles in Press |
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2022-04-21 17:42 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-05-13 04:06 |
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Publish the Manuscript Online |
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2022-06-02 10:05 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Hematology |
| Manuscript Type |
Case Report |
| Article Title |
Pediatric acute myeloid leukemia patients with i(17)(q10) mimicking acute promyelocytic leukemia: Two case reports
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hong-Xia Yan, Wei-Hua Zhang, Jin-Quan Wen, Yan-He Liu, Bao-Juan Zhang and A-Duo Ji |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jin-Quan Wen, BSc, N/A, N/A, Department of Pediatric Hematology/Oncology, Rainbow Hospital of Xianyang (Children's Hospital of Xianyang), Rainbow Hospital of Xianyang (Children's Hospital of Xianyang), Xianyang Shanxi, China, Xianyang 721000, Shaanxi Province, China. wenjinquandr@126.com |
| Key Words |
Chromosome; i(17)(q10); Gene mutations; Acute promyelocytic leukemia; Acute myeloid leukemia; Case report |
| Core Tip |
Herein we reported two cases of AML mimicking APL after the same treatment protocols. A rare chromosomal abnormality, i(17)(q10), was observed in two pediatric patients, which mimicked APL phenotype. Both patients showed no responses to ATRA and ATO induction therapy. One patient with i(17)(q10) died after 5 months, and the other patient with i(17)(q10) add (14)14 had been medication free more than 10 months and achieved complete tumor remission for 3 years since drugs were withdrawn. Pediatric AML mimicking APL is difficult to treat and additional cases should be studied to provide better treatment strategies for these patients. |
| Publish Date |
2022-06-02 10:05 |
| Citation |
Yan HX, Zhang WH, Wen JQ, Liu YH, Zhang BJ, Ji AD. Pediatric acute myeloid leukemia patients with i(17)(q10) mimicking acute promyelocytic leukemia: Two case reports. World J Clin Cases 2022; 10(16): 5446-5455 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i16/5446.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i16.5446 |
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