Publication Name	World Journal of Gastroenterology
Manuscript ID	72283
Country	India

Received	2021-10-11 04:50
Peer-Review Started	2021-10-11 04:51
To Make the First Decision
Return for Revision	2021-11-15 21:52
Revised	2021-11-30 09:08
Second Decision	2022-06-13 03:14
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-06-20 03:47
Articles in Press	2022-06-20 03:47
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-05-30 08:40
Typeset the Manuscript	2022-06-22 06:02
Publish the Manuscript Online	2022-07-13 07:30

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Radiology, Nuclear Medicine & Medical Imaging
Manuscript Type	Review
Article Title	Advances in the imaging of gastroenteropancreatic neuroendocrine neoplasms
Manuscript Source	Invited Manuscript
All Author List	Anupama Ramachandran and Kumble Seetharama Madhusudhan
ORCID	Author(s) ORCID Number Anupama Ramachandran http://orcid.org/0000-0002-5808-6076 Kumble Seetharama Madhusudhan http://orcid.org/0000-0001-8806-2625
Funding Agency and Grant Number
Corresponding Author	Kumble Seetharama Madhusudhan, MD, Additional Professor, Radiodiagnosis and Interventional Radiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India. drmadhuks@gmail.com
Key Words	Neuroendocrine tumor; Gastroenteropancreatic; Intravoxel incoherent motion; Diffusion weighted imaging; Perfusion imaging; Dual energy computed tomography
Core Tip	The prognosis of gastroenteropancreatic neuroendocrine neoplasms (GEPNENs) depends on the stage of the disease and tumor grade. Traditional imaging techniques like multiphase contrast enhanced computed tomography perform well at disease staging. For tumor grading, histopathological examination, with determination of number of mitoses and Ki-67 index is considered optimal. Advances in imaging techniques have enabled detection of smaller neuroendocrine neoplasms (< 2 cm). By analysing functional information like diffusion, perfusion and tumor heterogeneity, quantitative imaging is currently focused on non-invasive prediction of the grade of GEPNENs preoperatively.
Publish Date	2022-07-13 07:30
Citation	Ramachandran A, Madhusudhan KS. Advances in the imaging of gastroenteropancreatic neuroendocrine neoplasms. World J Gastroenterol 2022; 28(26): 3008-3026
URL	https://www.wjgnet.com/1007-9327/full/v28/i26/3008.htm
DOI	https://dx.doi.org/10.3748/wjg.v28.i26.3008

Full Article (PDF)	WJG-28-3008.pdf
Full Article (Word)	WJG-28-3008.docx
Manuscript File	72283_Auto_Edited_LM.docx
Answering Reviewers	72283-Answering reviewers.pdf
Audio Core Tip	72283-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	72283-Conflict-of-interest statement.pdf
Copyright License Agreement	72283-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	72283-Language certificate.pdf
Peer-review Report	72283-Peer-review(s).pdf
Scientific Editor Work List	72283-Scientific editor work list.pdf
CrossCheck Report	72283-CrossCheck report.pdf