| ISSN |
1949-8470 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Immunosuppressive treatment and radiotherapy in kidney transplant patients: A systematic review
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Valentina Lancellotta, Andrea D'Aviero, Bruno Fionda, Calogero Casà, Ilaria Esposito, Francesco Preziosi, Anna Acampora, Fabio Marazzi, György Kovács, Barbara Alicja Jereczek-Fossa, Alessio Giuseppe Morganti, Vincenzo Valentini, Maria Antonietta Gambacorta, Jacopo Romagnoli and Luca Tagliaferri |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Bruno Fionda, MD, Doctor, UOC Radioterapia Oncologica, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Agostino Gemelli 8, Rome 00168, Rome, Italy. bruno.fionda@yahoo.it |
| Key Words |
Renal transplant patients; Graft rejection; Immunosuppression; Radiotherapy; Survival |
| Core Tip |
This systematic review aimed to define the need of immunosuppressive therapy modulation during radiotherapy. There is still no clear evidence that withdrawing antimetabolites and/or calcineurin inhibitors and/or mammalian target of rapamycin-inhibitors improves patient survival in kidney transplant recipients with cancer undergoing radiotherapy. Even where immunosuppression therapy was described, patient survival seemed to be correlated only with cancer stage and type. The results of this systematic review do not support the reduction of immunosuppression dose in patients undergoing radiotherapy. |
| Publish Date |
2022-03-25 07:47 |
| Citation |
Lancellotta V, D'Aviero A, Fionda B, Casà C, Esposito I, Preziosi F, Acampora A, Marazzi F, Kovács G, Jereczek-Fossa BA, Morganti AG, Valentini V, Gambacorta MA, Romagnoli J, Tagliaferri L. Immunosuppressive treatment and radiotherapy in kidney transplant patients: A systematic review. World J Radiol 2022; 14(3): 60-69 |
| URL |
https://www.wjgnet.com/1949-8470/full/v14/i3/60.htm |
| DOI |
https://dx.doi.org/10.4329/wjr.v14.i3.60 |
