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Articles Published Processes
3/11/2022 12:39:21 AM | Browse: 378 | Download: 924
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Received |
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2021-10-11 10:20 |
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Peer-Review Started |
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2021-10-11 10:20 |
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To Make the First Decision |
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Return for Revision |
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2021-11-11 02:59 |
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Revised |
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2021-11-27 11:03 |
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Second Decision |
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2022-01-27 03:34 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-01-29 07:01 |
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Articles in Press |
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2022-01-29 07:01 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-01-24 04:19 |
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Typeset the Manuscript |
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2022-02-23 08:51 |
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Publish the Manuscript Online |
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2022-03-11 00:39 |
ISSN |
2307-8960 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Respiratory System |
Manuscript Type |
Case Control Study |
Article Title |
Analysis of bacterial spectrum, activin A, and CD64 in chronic obstructive pulmonary disease patients complicated with pulmonary infections
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Zhao-Yang Fei, Jiang Wang, Jie Liang, Xue Zhou and Min Guo |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Zhao-Yang Fei, MM, Associate Chief Physician, Experimental Research Centre, The First Affiliated Hospital of Chongqing Medical University, No. 1, Xueyuan Road, Yuzhong District, Chongqing 400010, China. feizhaoyangwy@163.com |
Key Words |
Chronic obstructive pulmonary disease; Infection; Activin A; CD64 index |
Core Tip |
This study explores the bacterial spectrum via analysis of activin A levels, CD64 index, and related mechanisms in COPD patients complicated with pulmonary infection. Based on our analyses, pulmonary infections in COPD patients are mainly caused by Streptococcus pneumoniae, Pseudomonas aeruginosa, and Klebsiella pneumoniae. Pulmonary infections can significantly increase neutrophil CD64 index and serum activin A levels, thereby activating the activin A/Smad3 signaling pathway, which may positively regulate the TLR4/MyD88/NFκB signaling pathway. |
Publish Date |
2022-03-11 00:39 |
Citation |
Fei ZY, Wang J, Liang J, Zhou X, Guo M. Analysis of bacterial spectrum, activin A, and CD64 in chronic obstructive pulmonary disease patients complicated with pulmonary infections. World J Clin Cases 2022; 2382-2392 |
URL |
https://www.wjgnet.com/2307-8960/full/v10/i8/2382.htm |
DOI |
https://dx.doi.org/10.12998/wjcc.v10.i8.2382 |
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