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Articles Published Processes
9/1/2014 12:00:00 PM | Browse: 1324 | Download: 1419
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Received |
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2013-11-09 11:27 |
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Peer-Review Started |
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2013-11-09 17:45 |
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First Decision by Editorial Office Director |
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Return for Revision |
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2013-12-10 20:24 |
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Revised |
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2013-12-20 04:54 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2014-01-14 19:14 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2014-01-14 20:05 |
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Articles in Press |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-02-15 16:55 |
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Publish the Manuscript Online |
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2014-02-19 15:19 |
| Category |
Infectious Diseases |
| Manuscript Type |
Minireviews |
| Article Title |
Hepatitis C virus infection and insulin resistance
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Sandip K Bose and Ranjit Ray |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Institutes of Health |
DK080812 |
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| Corresponding Author |
Ranjit Ray, PhD, Division of Infectious Diseases, Allergy and Immunology, Edward A Doisy Research Center, 1100 S. Grand Blvd., 8th Floor, St. Louis, MO 63104, United States. rayr@slu.edu |
| Key Words |
Hepatitis C virus; Insulin resistance; Insulin receptor substrate 1; Protein kinase B; mammalian target of rapamycin/S6K1; Suppressor of cytokine signaling 3; Glucose transporter-4; Lipid metabolism; Antiviral therapy |
| Core Tip |
Insulin resistance is one of the pathological features in patients with hepatitis C virus (HCV) infection and often leads to development of type Ⅱ diabetes. Recent evidence indicates that HCV associated insulin resistance may result in hepatic fibrosis, steatosis, hepatocellular carcinoma and resistance to anti-viral treatment. In this review, we summarize the available information on how HCV infection interferes with insulin signaling pathways. |
| Publish Date |
2014-02-19 15:19 |
| Citation |
Bose SK, Ray R. Hepatitis C virus infection and insulin resistance. World J Diabetes 2014; 5(1): 52-58 Available from: URL: http://www.wjgnet.com/1948-9358/full/v5/i1/52.htm DOI: http:// dx.doi.org/10.4239/wjd.v5.i1.52 |
| URL |
http://www.wjgnet.com/1948-9358/full/v5/i1/52.htm |
| DOI |
http://dx.doi.org/10.4239/wjd.v5.i1.52 |
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