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8/26/2014 4:48:00 PM | Browse: 827 | Download: 629
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 7237
Country United States
Received
2013-11-10 12:37
Peer-Review Started
2013-11-10 19:54
To Make the First Decision
2014-02-13 16:29
Return for Revision
2014-02-20 20:03
Revised
2014-03-26 04:12
Second Decision
2014-05-14 16:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-05-14 16:44
Articles in Press
2014-05-23 12:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-06-13 14:00
Publish the Manuscript Online
2014-06-20 15:55
ISSN 1948-5204 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Monoclonal antibodies that target the immunogenic proteins expressed in colorectal cancer
Manuscript Source Invited Manuscript
All Author List Myron Arlen, Philip Arlen, Gene Coppa, Jim Crawford, XuePing Wang, Olga Saric, Alex Dubeykovskiy and Ernesto Molmenti
Funding Agency and Grant Number
Corresponding Author Myron Arlen, MD, Manhasset NY and Precision Biologics, 445 Northern Blvd, Great Neck, NY 11021, United States. marlenmd@msn.com
Key Words Colorectal cancer; Monoclonal antibodies; Immunohistochemistry; Antibody dependent cell cytotoxicity; Tumor associated antigens
Core Tip The ideal monoclonal antibody to be employed in cancer management is one targeting an immunogenic protein expressed in a specific cancer system. Those presently employed in cancer management, target a growth factor or carbohydrate antigen seen in both cancer and normal tissue. Their value as such is limited. The monoclonals described herein are directed against colon cancer tumor associated antigen and have value in both diagnostic and therapeutic uses for controlling this disease.
Publish Date 2014-06-20 15:55
Citation Arlen M, Arlen P, Coppa G, Crawford J, Wang X, Saric O, Dubeykovskiy A, Molmenti E. Monoclonal antibodies that target the immunogenic proteins expressed in colorectal cancer. World J Gastrointest Oncol 2014; 6(6): 170-176
URL http://www.wjgnet.com/1948-5204/full/v6/i6/170.htm
DOI http://dx.doi.org/10.4251/wjgo.v6.i6.170
Full Article (PDF) WJGO-6-170.pdf
Full Article (Word) WJGO-6-170.doc
Manuscript File 7237-Review.doc
Answering Reviewers 7237-Answering reviewers.pdf
Copyright License Agreement 7237-Copyright assignment.pdf
Peer-review Report 7237-Peer review(s).pdf
Scientific Editor Work List 7237-Scientific editor work list.pdf