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Articles Published Processes
8/26/2014 4:48:00 PM | Browse: 920 | Download: 777
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Received |
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2013-11-10 12:37 |
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Peer-Review Started |
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2013-11-10 19:54 |
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To Make the First Decision |
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2014-02-13 16:29 |
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Return for Revision |
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2014-02-20 20:03 |
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Revised |
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2014-03-26 04:12 |
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Second Decision |
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2014-05-14 16:30 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-05-14 16:44 |
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Articles in Press |
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2014-05-23 12:19 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-06-13 14:00 |
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Publish the Manuscript Online |
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2014-06-20 15:55 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Minireviews |
Article Title |
Monoclonal antibodies that target the immunogenic proteins expressed in colorectal cancer
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Manuscript Source |
Invited Manuscript |
All Author List |
Myron Arlen, Philip Arlen, Gene Coppa, Jim Crawford, XuePing Wang, Olga Saric, Alex Dubeykovskiy and Ernesto Molmenti |
Funding Agency and Grant Number |
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Corresponding Author |
Myron Arlen, MD, Manhasset NY and Precision Biologics, 445 Northern Blvd, Great Neck, NY 11021, United States. marlenmd@msn.com |
Key Words |
Colorectal cancer; Monoclonal antibodies; Immunohistochemistry; Antibody dependent cell cytotoxicity; Tumor associated antigens |
Core Tip |
The ideal monoclonal antibody to be employed in cancer management is one targeting an immunogenic protein expressed in a specific cancer system. Those presently employed in cancer management, target a growth factor or carbohydrate antigen seen in both cancer and normal tissue. Their value as such is limited. The monoclonals described herein are directed against colon cancer tumor associated antigen and have value in both diagnostic and therapeutic uses for controlling this disease. |
Publish Date |
2014-06-20 15:55 |
Citation |
Arlen M, Arlen P, Coppa G, Crawford J, Wang X, Saric O, Dubeykovskiy A, Molmenti E. Monoclonal antibodies that target the immunogenic proteins expressed in colorectal cancer. World J Gastrointest Oncol 2014; 6(6): 170-176 |
URL |
http://www.wjgnet.com/1948-5204/full/v6/i6/170.htm |
DOI |
http://dx.doi.org/10.4251/wjgo.v6.i6.170 |
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