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Articles Published Processes
8/16/2022 11:09:42 AM | Browse: 300 | Download: 835
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Received |
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2021-10-15 13:57 |
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Peer-Review Started |
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2021-10-15 13:58 |
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To Make the First Decision |
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Return for Revision |
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2022-01-11 02:45 |
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Revised |
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2022-02-04 23:13 |
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Second Decision |
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2022-08-01 03:08 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-08-05 22:01 |
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Articles in Press |
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2022-08-05 22:01 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-08-12 05:45 |
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Publish the Manuscript Online |
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2022-08-16 11:09 |
| ISSN |
2218-5836 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Prospective Study |
| Article Title |
Quantitative alpha-defensin testing: Is synovial fluid dilution important?
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Rodrigo Calil Teles Abdo, Riccardo Gomes Gobbi, Chilan Bou Ghosson Leite, Sandra Gofinet Pasoto, Elaine Pires Leon, Ana Lucia Lei Munhoz Lima, Eloisa Bonfa, José Ricardo Pécora and Marco Kawamura Demange |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Fundação de Amparo à Pesquisa do Estado de São Paulo |
2017/25540-9 |
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| Corresponding Author |
Rodrigo Calil Teles Abdo, MD, Surgeon, Instituto de Ortopedia e Traumatologia, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, R. Dr. Ovídio Pires de Campos, 333 - Cerqueira César., Sao Paulo 05403-010, SP, Brazil. rctabdo@gmail.com |
| Key Words |
Alpha-defensin; Enzyme-linked immunosorbent assay; Periprosthetic joint infection; Laboratory findings |
| Core Tip |
Alpha-defensin is an antimicrobial peptide widely studied in patients with periprosthetic joint infection. Indeed, the analysis of alpha-defensin concentration in the synovial fluid by enzyme-linked immunosorbent assay (ELISA) has been gaining ground. However, there is a lack of information regarding the detailed technique for synovial fluid ELISA, particularly in regard to its dilution. Therefore, this study analyzed the influence of dilution in synovial fluid samples for the alpha-defensin ELISA method. We presume that this novel information may be helpful to make ELISA more reproducible and widely accessible for different treatment centers worldwide. |
| Publish Date |
2022-08-16 11:09 |
| Citation |
Abdo RCT, Gobbi RG, Leite CBG, Pasoto SG, Leon EP, Lima ALLM, Bonfa E, Pécora JR, Demange MK. Quantitative alpha-defensin testing: is synovial fluid dilution important? World J Orthop 2022; 13(8): 760-767 |
| URL |
https://www.wjgnet.com/2218-5836/full/v13/i8/760.htm |
| DOI |
https://dx.doi.org/10.5312/wjo.v13.i8.760 |
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