Publication Name	World Journal of Gastroenterology
Manuscript ID	72466
Country	Italy

Received	2022-03-24 23:27
Peer-Review Started	2022-03-24 23:29
To Make the First Decision
Return for Revision	2022-05-09 06:55
Revised	2022-05-18 21:14
Second Decision	2022-07-22 07:47
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-07-25 00:47
Articles in Press	2022-07-25 00:47
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-07-19 03:32
Typeset the Manuscript	2022-07-29 01:00
Publish the Manuscript Online	2022-08-16 11:59

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
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Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Review
Article Title	Early diagnosis of pancreatic cancer: What strategies to avoid a foretold catastrophe
Manuscript Source	Invited Manuscript
All Author List	Valeria Tonini and Manuel Zanni
ORCID	Author(s) ORCID Number Valeria Tonini http://orcid.org/0000-0003-3130-2928 Manuel Zanni http://orcid.org/0000-0001-7732-7739
Funding Agency and Grant Number
Corresponding Author	Valeria Tonini, MD, PhD, Adjunct Associate Professor, Professor, Surgeon, Surgical Oncologist, Department of Medical and Surgical Sciences, University of Bologna, Via Massarenti 9, Bologna 40138, Italy. valeria.tonini@unibo.it
Key Words	Pancreatic cancer; Pancreatic ductal adenocarcinoma; Early diagnosis; Liquid biopsy; Pancreatic cancer biomarkers; Artificial intelligence; Pancreatic cancer screening
Core Tip	Pancreatic ductal adenocarcinoma is one of the solid neoplasms with the worst prognosis. Surgical resection is the only potentially curative treatment. In 80% of patients, pancreatic ductal adenocarcinoma is discovered at a stage too advanced for surgery. The aim of this review was to summarize all the possible strategies available today for the early diagnosis of pancreatic ductal adenocarcinoma and the paths that research must take to make this goal ever closer. The article highlights the urgency of devoting more attention and resources to this pathology in order to reach a solution that seems more and more unreachable every day.
Publish Date	2022-08-16 11:59
Citation	Tonini V, Zanni M. Early diagnosis of pancreatic cancer: What strategies to avoid a foretold catastrophe. World J Gastroenterol 2022; 28(31): 4235-4248
URL	https://www.wjgnet.com/1007-9327/full/v28/i31/4235.htm
DOI	https://dx.doi.org/10.3748/wjg.v28.i31.4235

Full Article (PDF)	WJG-28-4235.pdf
Full Article (Word)	WJG-28-4235.docx
Manuscript File	72466_Auto_Edited-YJM-Filipodia-LS.docx
Answering Reviewers	72466-Answering reviewers.pdf
Audio Core Tip	72466-Audio core tip.aac
Conflict-of-Interest Disclosure Form	72466-Conflict-of-interest statement.pdf
Copyright License Agreement	72466-Copyright license agreement.pdf
Peer-review Report	72466-Peer-review(s).pdf
Scientific Editor Work List	72466-Scientific editor work list.pdf
CrossCheck Report	72466-CrossCheck report.pdf