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Articles Published Processes
8/27/2014 4:30:00 PM | Browse: 774 | Download: 683
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Received |
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2013-11-11 10:41 |
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Peer-Review Started |
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2013-11-12 12:24 |
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To Make the First Decision |
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2013-12-10 15:05 |
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Return for Revision |
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2013-12-17 17:28 |
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Revised |
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2013-12-25 04:42 |
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Second Decision |
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2014-01-16 14:27 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-01-16 14:45 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-02-26 11:19 |
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Publish the Manuscript Online |
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2014-03-19 21:35 |
Category |
Cardiac & Cardiovascular Systems |
Manuscript Type |
Review |
Article Title |
MicroRNA signature and function in retinal neovascularization
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Manuscript Source |
Invited Manuscript |
All Author List |
Saloni Agrawal and Brahim Chaqour |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Eye Institute of the National Institutes of Health |
EY022091-01 (to Chaqour B) |
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Corresponding Author |
Brahim Chaqour, Professor, Department of Cell Biology and Ophthalmology, and SUNY Eye Institute Downstate Medical Center, 450 Clarkson Avenue 5, Brooklyn, NY 11203, United States. bchaqour@downstate.edu |
Key Words |
MircoRNA; Angiogenesis; Retinal neovascularization; Vascular endothelial growth factor; Ischemia; Endothelial cell |
Core Tip |
This review examines the critical regulatory role of microRNAs (miRNAs) in the process of normal and pathological angiogenesis and the prospects that they provide for the development of new treatments. miRNAs are both upstream and downstream of multiple growth factors in regulating endothelial proliferation, migration, and vascular patterning, processes critical for normal and abnormal formation of blood vessels. Emphasis in this review is placed on how specific vascular-enriched miRNAs regulate cell responses to various cues by targeting several factors, receptors and/or signaling molecules in order to maintain either vascular function or dysfunction. |
Publish Date |
2014-03-19 21:35 |
Citation |
Agrawal S, Chaqour B. MicroRNA signature and function in retinal neovascularization. World J Biol Chem 2014; 5(1): 1-11 Available from: URL: http://www.wjgnet.com/1949-8454/full/v5/i1/1.htm DOI: http://dx.doi.org/10.4331/wjbc.v5.i1.1 |
URL |
http://www.wjgnet.com/1949-8454/full/v5/i1/1.htm |
DOI |
http://dx.doi.org/10.4331/wjbc.v5.i1.1 |
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