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Articles Published Processes
5/25/2022 8:33:35 AM | Browse: 412 | Download: 1097
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Received |
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2021-10-25 15:18 |
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Peer-Review Started |
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2021-10-25 15:20 |
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To Make the First Decision |
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Return for Revision |
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2021-12-28 01:22 |
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Revised |
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2022-01-19 12:31 |
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Second Decision |
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2022-04-08 02:16 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-04-09 19:15 |
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Articles in Press |
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2022-04-09 19:15 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-03-31 21:11 |
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Typeset the Manuscript |
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2022-05-06 01:21 |
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Publish the Manuscript Online |
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2022-05-25 08:33 |
| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Surgery |
| Manuscript Type |
Minireviews |
| Article Title |
Role of surgical treatments in high-grade or advanced gastroenteropancreatic neuroendocrine neoplasms
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Qing-Yang Que, Lin-Cheng Zhang, Jia-Qi Bao, Sun-Bin Ling and Xiao Xu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| State Key Program of National Natural Science Foundation of China |
81930016 |
| Zhejiang Provincial Natural Science Foundation of China |
LY21H160026 |
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| Corresponding Author |
Xiao Xu, FACS, MD, PhD, Academic Fellow, Chief Doctor, Professor, NA, Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, No. 261 Huansha Road, Hangzhou 310006, Zhejiang Province, China. zjxu@zju.edu.cn |
| Key Words |
Gastroenteropancreatic neuroendocrine neoplasms; Neuroendocrine carcinomas; Surgery; Hepatic debulking; Liver transplant; Transplant oncology |
| Core Tip |
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) encompass a heterogeneous group of tumors with unique indolent biological behavior. The role of surgery in high-grade or advanced GEP-NENs is still controversial. There are several highlights of this review. First, we address the surgical benefits of selected high-grade GEP-NENs and summarize the tumor biological markers correlated with a prognosis. Second, we review various surgical strategies, including curative resection, debulking, resection after neoadjuvant therapy for metastatic GEP-NENs, and the latest clinical evidence. Finally, liver transplantation presents a curative therapeutic option for GEP-NEN patients with liver metastasis. We summarize the new findings and propose directions for future development. |
| Publish Date |
2022-05-25 08:33 |
| Citation |
Que QY, Zhang LC, Bao JQ, Ling SB, Xu X. Role of surgical treatments in high-grade or advanced gastroenteropancreatic neuroendocrine neoplasms. World J Gastrointest Surg 2022; 14(5): 397-408 |
| URL |
https://www.wjgnet.com/1948-9366/full/v14/i5/397.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v14.i5.397 |
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