Publication Name	World Journal of Methodology
Manuscript ID	72756
Country	Italy

Received	2021-10-26 18:40
Peer-Review Started	2021-10-26 18:41
To Make the First Decision
Return for Revision	2021-12-17 09:07
Revised	2021-12-18 00:04
Second Decision	2022-03-07 06:06
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-03-17 04:36
Articles in Press	2022-03-17 04:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-04-15 02:51
Publish the Manuscript Online	2022-05-19 00:49

ISSN	2222-0682 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Microscopy
Manuscript Type	Observational Study
Article Title	Lutetium in prostate cancer: Reconstruction of patient-level data from published trials and generation of a multi-trial Kaplan-Meier curve
Manuscript Source	Unsolicited Manuscript
All Author List	Andrea Messori
ORCID	Author(s) ORCID Number Andrea Messori http://orcid.org/0000-0002-5829-107X
Funding Agency and Grant Number
Corresponding Author	Andrea Messori, PharmD, Senior Researcher, HTA, ESTAR Toscana and Regione Toscana, via Alderotti 26/N, Firenze 50139, Italia, Italy. andrea.messori.it@gmail.com
Key Words	Survival analysis; Individual patient data reconstruction; Kaplan-Meier curves; Meta-analysis; Prostate Cancer; Lutetium
Core Tip	This paper describes the application of a new technique of individual-patient data reconstruction (IPDfromKM) to the progression-free survival curves published in two trials evaluating lutetium in metastatic prostate cancer. Our analysis interpreted these survival data and showed discordant results between the two trials, that need to be addressed by further clinical research.
Publish Date	2022-05-19 00:49
Citation	Messori A. Lutetium in prostate cancer: Reconstruction of patient-level data from published trials and generation of a multi-trial Kaplan-Meier curve. World J Methodol 2022; 12(3): 107-112
URL	https://www.wjgnet.com/2222-0682/full/v12/i3/107.htm
DOI	https://dx.doi.org/10.5662/wjm.v12.i3.107

Full Article (PDF)	WJM-12-107.pdf
Full Article (Word)	WJM-12-107.docx
Manuscript File	72756_Auto_Edited-YXX.docx
Answering Reviewers	72756-Answering reviewers.pdf
Audio Core Tip	72756-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	72756-Conflict-of-interest statement.pdf
Copyright License Agreement	72756-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	72756-Language certificate.pdf
Peer-review Report	72756-Peer-review(s).pdf
Scientific Misconduct Check	72756-Bing Xing YX-2.png
Scientific Editor Work List	72756-Scientific editor work list.pdf
CrossCheck Report	72756-CrossCheck report.pdf