| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Neoadjuvant transcatheter arterial chemoembolization and systemic chemotherapy for the treatment of undifferentiated embryonal sarcoma of the liver in children
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Min He, Jia-Bin Cai, Can Lai, Jun-Qing Mao, Jie-Ni Xiong, Zhong-Hai Guan, Lin-Jie Li, Qiang Shu, Mei-Dan Ying and Jin-Hu Wang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Youth Program of Natural Science Foundation of Zhejiang Province |
LQ20H160027 |
| National Natural Science Foundation of China |
U20A20137 |
|
| Corresponding Author |
Jin-Hu Wang, MD, PhD, Chief Doctor, Director, Director, Surgical Oncologist, Department of Surgical Oncology, The Children’s Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, No. 3333 Binsheng Road, Hangzhou 310052, Zhejiang Province, China. wjh@zju.edu.cn |
| Key Words |
Undifferentiated embryonal sarcoma of the liver; Unresectable; Neoadjuvant therapy; Transcatheter arterial chemoembolization; Systemic chemotherapy |
| Core Tip |
Undifferentiated embryonal sarcoma of the liver (UESL) is a rare and aggressive mesenchymal tumor in children. The prognosis of UESL has previously been considered poor. Modern multimodal treatment and supportive therapy have improved survival. Complete tumor excision plays the central role in the treatment of UESL. In this study, we analyzed our single-center data of children with UESL who received neoadjuvant therapy (NAT) between January 2004 and December 2019, and found that NAT effectively reduced tumor volume, cleared tumor margin, and caused massive tumor necrosis. It may provide a promising choice for successful operation of UESL in children. |
| Publish Date |
2022-06-24 09:00 |
| Citation |
He M, Cai JB, Lai C, Mao JQ, Xiong JN, Guan ZH, Li LJ, Shu Q, Ying MD, Wang JH. Neoadjuvant transcatheter arterial chemoembolization and systemic chemotherapy for the treatment of undifferentiated embryonal sarcoma of the liver in children. World J Clin Cases 2022; 10(19): 6437-6445 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i19/6437.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i19.6437 |
