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Articles Published Processes
3/15/2022 2:23:07 PM | Browse: 817 | Download: 1978
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Received |
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2021-10-30 14:36 |
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Peer-Review Started |
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2021-10-30 14:38 |
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First Decision by Editorial Office Director |
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2021-12-27 06:52 |
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Return for Revision |
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2021-12-27 06:52 |
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Revised |
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2022-01-29 03:32 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2022-02-21 07:23 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2022-02-23 20:54 |
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Articles in Press |
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2022-02-23 20:54 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-03-08 18:00 |
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Publish the Manuscript Online |
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2022-03-15 14:23 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Case Control Study |
| Article Title |
Functional annotation and enrichment analysis of differentially expressed serum proteins in patients with type 2 diabetes after dapagliflozin
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yan-Xue Zhao, Sarul Borjigin and Zhao-Li Yan |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Major Scientific Research Program of the Affiliated Hospital of Inner Mongolia Medical University |
NYFY ZD 001 |
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| Corresponding Author |
Zhao-Li Yan, MD, Professor, Department of Endocrinology, The Affiliated Hospital of Inner Mongolia Medical University, No. 1 Tongdao North Road, Huimin District, Hohhot 010000, Inner Mongolia Autonomous Region, China. aliceyzl@163.com |
| Key Words |
Type 2 diabetes mellitus; Dapagliflozin; Non-standard quantitative proteomics; Myeloperoxidase; Alpha II B integrin; Podocalyxin |
| Core Tip |
This study aimed to identify differentially expressed proteins associated with dapagliflozin treatment in patients with type 2 diabetes mellitus. Changes in blood indexes were examined in 20 patients treated with dapagliflozin for 3 mo. Quantitative proteomics was used to identify differentially expressed proteins using the serum samples of five patients. Dapagliflozin has hypoglycemic effects and regulates the serum expressions of myeloperoxidase, alpha II B integrin, and podocalyxin, possibly contributing to the effects of dapagliflozin on oxidative stress, insulin resistance, and lipid metabolism. |
| Publish Date |
2022-03-15 14:23 |
| Citation |
Zhao YX, Borjigin S, Yan ZL. Functional annotation and enrichment analysis of differentially expressed serum proteins in patients with type 2 diabetes after dapagliflozin. World J Diabetes 2022; 13(3): 224-239 |
| URL |
https://www.wjgnet.com/1948-9358/full/v13/i3/224.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v13.i3.224 |
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