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Articles Published Processes
4/8/2022 12:06:56 PM | Browse: 290 | Download: 622
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Received |
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2021-11-05 13:40 |
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Peer-Review Started |
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2021-11-05 13:41 |
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To Make the First Decision |
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Return for Revision |
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2021-12-27 08:03 |
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Revised |
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2022-01-29 12:30 |
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Second Decision |
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2022-02-24 06:10 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-02-27 19:11 |
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Articles in Press |
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2022-02-27 19:11 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-03-29 09:19 |
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Publish the Manuscript Online |
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2022-04-08 12:06 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Case Report |
| Article Title |
Cytochrome P450 family 17 subfamily A member 1 mutation causes severe pseudohermaphroditism: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yu Gong, Fang Qin, Wen-Jia Li, Le-Yu Li, Ping He and Xing-Jian Zhou |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Xing-Jian Zhou, MD, Chief Doctor, Department of Endocrine and Metabolism, Xiangyang No. 1 People's Hospital, Hubei University of Medicine, No. 15 Jiefang Road, Fancheng District, Xiangyang 441000, Hubei Province, China. hazck147@163.com |
| Key Words |
Congenital adrenal cortex hyperplasia; Cytochrome P450 family 17 subfamily A member 1; 17α-Hydroxylase deficiency; Pseudohermaphroditism; Case report |
| Core Tip |
17α-Hydroxylase deficiency (17-OHD) is a rare form of congenital adrenal hyperplasia, characterized by hypertension, hypokalemia, and gonadal dysplasia. We report a case of 17-OHD admitted to our hospital due to limb weakness. The patient’s blood pressure was difficult to control with various antihypertensive drugs. Her gonadal development was found to be abnormal, and chromosome analysis demonstrated karyotype 46,XY. The diagnosis was confirmed by the cytochrome P450 family 17 subfamily A member 1 (CYP17A1) test. The clinical manifestations of 17-OHD are complex. Hormone determination, imaging examination, chromosome determination and CYP17A1 gene detection are helpful for early diagnosis. |
| Publish Date |
2022-04-08 12:06 |
| Citation |
Gong Y, Qin F, Li WJ, Li LY, He P, Zhou XJ. Cytochrome P450 family 17 subfamily A member 1 mutation causes severe pseudohermaphroditism: A case report. World J Clin Cases 2022; 10(11): 3553-3560 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i11/3553.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i11.3553 |
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