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9/29/2022 10:42:42 AM | Browse: 304 | Download: 1184
Publication Name World Journal of Gastroenterology
Manuscript ID 72984
Country China
Received
2021-11-22 01:40
Peer-Review Started
2021-11-22 01:42
To Make the First Decision
Return for Revision
2022-01-11 01:24
Revised
2022-01-24 09:10
Second Decision
2022-09-09 03:35
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-09-12 17:44
Articles in Press
2022-09-12 17:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
2022-09-07 13:45
Typeset the Manuscript
2022-09-25 23:40
Publish the Manuscript Online
2022-09-29 10:42
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Lentivirus-mediated short hairpin RNA interference of CENPK inhibits growth of colorectal cancer cells with overexpression of Cullin 4A
Manuscript Source Unsolicited Manuscript
All Author List Xian Li, Yi-Ru Han, Xuefeng Xuefeng, Yong-Xiang Ma, Guo-Sheng Xing, Zhi-Wen Yang, Zhen Zhang, Lin Shi and Xin-Lin Wu
ORCID
Author(s) ORCID Number
Xian Li http://orcid.org/0000-0002-9107-5096
Yi-Ru Han http://orcid.org/0000-0001-8245-9533
Xuefeng Xuefeng http://orcid.org/0000-0002-5058-5735
Yong-Xiang Ma http://orcid.org/0000-0002-1027-0093
Guo-Sheng Xing http://orcid.org/0000-0002-5183-7607
Zhi-Wen Yang http://orcid.org/0000-0001-6502-3850
Zhen Zhang http://orcid.org/0000-0002-5281-7067
Lin Shi http://orcid.org/0000-0001-6543-8650
Xin-Lin Wu http://orcid.org/0000-0002-2860-4477
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81860416, 22168028
Inner Mongolia Autonomous Region Grassland Talent Innovation Talent Team Fund 2019
Inner Mongolia Natural Science Fund 2021MS02005
Corresponding Author Xin-Lin Wu, Doctor, Chief Doctor, Department of Gastrointestinal Surgery, The Affiliated Hospital of Inner Mongolia Medical University, No. 1, North Street, Hohhot 010050, Inner Mongolia Autonomous Region, China. wuxinlin@126.com
Key Words Colorectal cancer; Centromere protein K; Bioinformatics analysis; Lentivirus-mediated short hairpin RNA interference; Cullin 4A
Core Tip High expression of centromere protein K (CENPK) in colorectal cancer (CRC) was found by immunohistochemistry. We demonstrated overexpression of CENPK in human colon cancer samples. CENPK was an independent risk factor in patients with CRC. Our findings indicate a potential role of CENPK in promoting tumor proliferation. CENPK may serve as a novel diagnostic and prognostic biomarker in patients with CRC.
Publish Date 2022-09-29 10:42
Citation Li X, Han YR, Xuefeng X, Ma YX, Xing GS, Yang ZW, Zhang Z, Shi L, Wu XL. Lentivirus-mediated short hairpin RNA interference of CENPK inhibits growth of colorectal cancer cells with overexpression of Cullin 4A. World J Gastroenterol 2022; 28(37): 5420-5443
URL https://www.wjgnet.com/1007-9327/full/v28/i37/5420.htm
DOI https://dx.doi.org/10.3748/wjg.v28.i37.5420
Full Article (PDF) WJG-28-5420.pdf
Full Article (Word) WJG-28-5420.docx
Manuscript File 72984_Auto_Edited-JJW-WangTQ-LS.docx
Answering Reviewers 72984-Answering reviewers.pdf
Audio Core Tip 72984-Audio core tip.m4a
Biostatistics Review Certificate 72984-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 72984-Conflict-of-interest statement.pdf
Copyright License Agreement 72984-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 72984-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 72984-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 72984-Language certificate.pdf
Supplementary Material 72984-Supplementary material.pdf
Peer-review Report 72984-Peer-review(s).pdf
Scientific Misconduct Check 72984-Bing-Wang JJ-2.png
Scientific Editor Work List 72984-Scientific editor work list.pdf