Publication Name	World Journal of Clinical Cases
Manuscript ID	73061
Country	China

Received	2021-11-18 03:29
Peer-Review Started	2021-11-18 03:31
To Make the First Decision
Return for Revision	2021-12-27 09:42
Revised	2022-02-21 07:00
Second Decision	2022-06-01 02:58
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-06-03 21:21
Articles in Press	2022-06-03 21:21
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-04-18 08:39
Typeset the Manuscript	2022-07-02 10:44
Publish the Manuscript Online	2022-07-11 08:36

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Anesthesiology
Manuscript Type	Randomized Clinical Trial
Article Title	Dexmededomidine in pediatric unilateral internal inguinal ring ligation
Manuscript Source	Unsolicited Manuscript
All Author List	Guang Liu, Ling Zhang, Hui-Se Wang, Yi Lin, Hong-Quan Jin, Xiao-Dan Wang, Wei-Na Qiao, Ya-Tao Zhang, Jiao-Qian Sun and Zhi-Na Liu
ORCID	Author(s) ORCID Number Guang Liu http://orcid.org/0000-0002-6349-9772 Ling Zhang http://orcid.org/0000-0003-0207-2676 Hui-Se Wang http://orcid.org/0000-0002-0125-5115 Yi Lin http://orcid.org/0000-0002-9303-7886 Hong-Quan Jin http://orcid.org/0000-0003-1439-5413 Xiao-Dan Wang http://orcid.org/0000-0002-2870-9359 Wei-Na Qiao http://orcid.org/0000-0001-7406-6465 Ya-Tao Zhang http://orcid.org/0000-0002-0413-6541 Jiao-Qian Sun http://orcid.org/0000-0002-1293-6231 Zhi-Na Liu http://orcid.org/0000-0001-9729-4081
Funding Agency and Grant Number
Corresponding Author	Zhi-Na Liu, N/A, Doctor, Doctor, Department of Anesthesiology, Baoding Children's Hospital, No. 3399 Hengxiang North Street, Baoding 071000, Hebei Province, China. wenwen9604@163.com
Key Words	Child; Dexmededomidine; Inguinal hernia; Pain management; Laparoscopy; Analgesics
Core Tip	This randomized controlled trial aimed to evaluate the safety and efficacy of dexmededomidine monotherapy in children who underwent laparoscopic unilateral internal inguinal ring ligation. A total of 390 children were included and randomly divided into a dexmededomidine group, a dexmededomidine + sufentanil group, and a sufentanil group. Our study suggested that the analgesic effects of dexmededomidine monotherapy were comparable to those of sufentanil alone or in combination with dexmededomidine for children who underwent laparoscopic unilateral internal inguinal ring ligation, and reported better sedative effects along with a significantly lower incidence of adverse events.
Publish Date	2022-07-11 08:36
Citation	Liu G, Zhang L, Wang HS, Lin Y, Jin HQ, Wang XD, Qiao WN, Zhang YT, Sun JQ, Liu ZN. Dexmededomidine in pediatric unilateral internal inguinal ring ligation. World J Clin Cases 2022; 10(21): 7376-7385
URL	https://www.wjgnet.com/2307-8960/full/v10/i21/7376.htm
DOI	https://dx.doi.org/10.12998/wjcc.v10.i21.7376

Full Article (PDF)	WJCC-10-7376.pdf
Full Article (Word)	WJCC-10-7376.docx
CONSORT 2010 Statement	73061-CONSORT-2010-Statement-revision.pdf
Manuscript File	73061_Auto_Edited-YXJW-WangTQ-LS.docx
Answering Reviewers	73061-Answering reviewers.pdf
Audio Core Tip	73061-Audio core tip.wav
Biostatistics Review Certificate	73061-Biostatistics statement.pdf
Clinical Trial Registration Statement	73061-Clinical trial registration statement.pdf
Conflict-of-Interest Disclosure Form	73061-Conflict-of-interest statement.pdf
Copyright License Agreement	73061-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	73061-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	73061-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	73061-Language certificate.pdf
Peer-review Report	73061-Peer-review(s).pdf
Scientific Misconduct Check	73061-Bing-Wu YXJ-2.png
Scientific Editor Work List	73061-Scientific editor work list.pdf
CrossCheck Report	73061-CrossCheck report.pdf