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Articles Published Processes
3/18/2022 12:26:44 PM | Browse: 639 | Download: 1456
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Received |
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2021-11-12 14:19 |
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Peer-Review Started |
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2021-11-12 14:21 |
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First Decision by Editorial Office Director |
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2021-12-12 07:42 |
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Return for Revision |
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2021-12-12 07:42 |
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Revised |
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2022-01-03 15:35 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2022-02-22 03:28 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2022-02-23 20:50 |
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Articles in Press |
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2022-02-23 20:50 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-03-09 02:02 |
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Publish the Manuscript Online |
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2022-03-18 12:26 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Genetics & Heredity |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Does COVID-19 increase the risk of neuropsychiatric sequelae? Evidence from a mendelian randomization approach
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Alfonsina Tirozzi, Federica Santonastaso, Giovanni de Gaetano, Licia Iacoviello and Alessandro Gialluisi |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Fondazione Umberto Veronesi |
NA |
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| Corresponding Author |
Licia Iacoviello, MD, PhD, Professor, Department of Epidemiology and Prevention, IRCCS NEUROMED, Department of Epidemiology and Prevention, IRCCS Istituto Neurologico Mediterraneo Neuromed, Via Atinense 18, Pozzilli 86077, Italy. licia.iacoviello@moli-sani.org |
| Key Words |
COVID-19; Sars-CoV-2; Neurological disorders; Neuropsychiatric disorders; Alzheimer’s disease; Anxiety; Mendelian randomization |
| Core Tip |
Inspired by suggestive findings of an increased incident risk of neurological and neuropsychiatric sequelae in people who have had coronavirus disease 2019 (COVID-19), we carried out a two-sample Mendelian randomization analysis to further investigate causality links and build evidence free of biases such as unmeasured confounding, residual reverse causality or lack of precision in electronic health record-based diagnoses. This analysis – typically applied to genetic associations from large genomic studies on the diseases of interest – indicated that the most severe forms of COVID-19 increased the risk of Alzheimer’s disease and anxiety, further supporting the findings of large observational studies. |
| Publish Date |
2022-03-18 12:26 |
| Citation |
Tirozzi A, Santonastaso F, de Gaetano G, Iacoviello L, Gialluisi A. Does COVID-19 increase the risk of neuropsychiatric sequelae? Evidence from a mendelian randomization approach. World J Psychiatry 2022; 12(3): 536-540 |
| URL |
https://www.wjgnet.com/2220-3206/full/v12/i3/536.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v12.i3.536 |
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