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3/18/2022 12:26:44 PM | Browse: 314 | Download: 476
Publication Name World Journal of Psychiatry
Manuscript ID 73108
Country/Territory Italy
Received
2021-11-12 14:19
Peer-Review Started
2021-11-12 14:21
To Make the First Decision
Return for Revision
2021-12-12 07:42
Revised
2022-01-03 15:35
Second Decision
2022-02-22 03:28
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-02-23 20:50
Articles in Press
2022-02-23 20:50
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-03-09 02:02
Publish the Manuscript Online
2022-03-18 12:26
ISSN 2220-3206 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Genetics & Heredity
Manuscript Type Letter to the Editor
Article Title Does COVID-19 increase the risk of neuropsychiatric sequelae? Evidence from a mendelian randomization approach
Manuscript Source Invited Manuscript
All Author List Alfonsina Tirozzi, Federica Santonastaso, Giovanni de Gaetano, Licia Iacoviello and Alessandro Gialluisi
ORCID
Author(s) ORCID Number
Alfonsina Tirozzi http://orcid.org/0000-0002-6052-1807
Federica Santonastaso http://orcid.org/0000-0001-7105-7504
Giovanni de Gaetano http://orcid.org/0000-0002-7823-1402
Licia Iacoviello http://orcid.org/0000-0003-0514-5885
Alessandro Gialluisi http://orcid.org/0000-0002-7388-4463
Funding Agency and Grant Number
Funding Agency Grant Number
Fondazione Umberto Veronesi NA
Corresponding Author Licia Iacoviello, MD, PhD, Professor, Department of Epidemiology and Prevention, IRCCS NEUROMED, Department of Epidemiology and Prevention, IRCCS Istituto Neurologico Mediterraneo Neuromed, Via Atinense 18, Pozzilli 86077, Italy. licia.iacoviello@moli-sani.org
Key Words COVID-19; Sars-CoV-2; Neurological disorders; Neuropsychiatric disorders; Alzheimer’s disease; Anxiety; Mendelian randomization
Core Tip Inspired by suggestive findings of an increased incident risk of neurological and neuropsychiatric sequelae in people who have had coronavirus disease 2019 (COVID-19), we carried out a two-sample Mendelian randomization analysis to further investigate causality links and build evidence free of biases such as unmeasured confounding, residual reverse causality or lack of precision in electronic health record-based diagnoses. This analysis – typically applied to genetic associations from large genomic studies on the diseases of interest – indicated that the most severe forms of COVID-19 increased the risk of Alzheimer’s disease and anxiety, further supporting the findings of large observational studies.
Publish Date 2022-03-18 12:26
Citation Tirozzi A, Santonastaso F, de Gaetano G, Iacoviello L, Gialluisi A. Does COVID-19 increase the risk of neuropsychiatric sequelae? Evidence from a mendelian randomization approach. World J Psychiatry 2022; 12(3): 536-540
URL https://www.wjgnet.com/2220-3206/full/v12/i3/536.htm
DOI https://dx.doi.org/10.5498/wjp.v12.i3.536
Full Article (PDF) WJP-12-536.pdf
Full Article (Word) WJP-12-536.docx
Manuscript File 73108_Auto_Edited.docx
Answering Reviewers 73108-Answering reviewers.pdf
Audio Core Tip 73108-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 73108-Conflict-of-interest statement.pdf
Copyright License Agreement 73108-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 73108-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 73108-Language certificate.pdf
Peer-review Report 73108-Peer-review(s).pdf
Scientific Misconduct Check 73108-Bing-Wu YXJ-2.png
Scientific Editor Work List 73108-Scientific editor work list.pdf