Publication Name	World Journal of Gastroenterology
Manuscript ID	7314
Country	Hungary

Received	2013-11-13 08:24
Peer-Review Started	2013-11-13 18:04
To Make the First Decision	2013-12-26 10:47
Return for Revision	2013-12-27 13:58
Revised	2014-01-16 04:09
Second Decision	2014-03-06 17:49
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-03-06 18:19
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-03-31 00:13
Typeset the Manuscript	2014-04-22 09:10
Publish the Manuscript Online	2014-05-07 10:10

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	New serological markers in pediatric patients with inflammatory bowel disease
Manuscript Source	Invited Manuscript
All Author List	Márta Kovács, Katalin Eszter Müller, Mária Papp, Péter László Lakatos, Mihály Csöndes and Gábor Veres
Funding Agency and Grant Number	Funding Agency Grant Number János Bolyai Research and Scholarship of the Hungarian Academy of Sciences OTKA-K 105530
Corresponding Author	Gábor Veres, MD, PhD, 1st Department of Pediatrics, Semmelweis University, 53 Bókay Street, 1083 Budapest, Hungary. veres.gabor@med.semmelweis-univ.hu
Key Words	Inflammatory bowel disease; Crohn’s disease; Ulcerative colitis; Pediatric; Serologic markers; Antimicrobial antibodies; Anti-glycan antibodies; Pancreatic antibodies; Inflammatory bowel disease
Core Tip	Application of non-invasive diagnostic tests for the diagnosis of inflammatory bowel disease (IBD) and differentiation between ulcerative colitis (UC) and Crohn’s disease (CD) would be useful in the pediatric population. The combination of pancreatic autoantibodies and antibodies against Saccharomyces cerevisiae antibodies/perinuclear cytoplasmic antibody improved the sensitivity of serological markers in pediatric patients with CD and UC. In addition, serologic markers for IBD can be applied to stratify IBD patients into more homogeneous subgroups with respect to disease progression. With this knowledge, clinicians will be able to stratify patients accordingly with regards to the risk of disease progression, create a personalized treatment strategy, and attempt to modify disease course, thereby improving long-term prognosis.
Publish Date	2014-05-07 10:10
Citation	Kovács M, Müller KE, Papp M, Lakatos PL, Csöndes M, Veres G. New serological markers in pediatric patients with inflammatory bowel disease. World J Gastroenterol 2014; 20(17): 4873-4882
URL	http://www.wjgnet.com/1007-9327/full/v20/i17/4873.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i17.4873

Full Article (PDF)	WJG-20-4873.pdf
Full Article (Word)	WJG-20-4873.doc
Manuscript File	7314-Review.doc
Answering Reviewers	7314-Answering reviewers.pdf
Copyright License Agreement	7314-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	7314-Language certificate.pdf
Peer-review Report	7314-Peer reviews.pdf
Scientific Editor Work List	7314-Scientific editor work list.doc