Publication Name	World Journal of Gastroenterology
Manuscript ID	7320
Country	Germany

Received	2013-11-13 08:41
Peer-Review Started	2013-11-14 10:44
To Make the First Decision	2013-12-26 10:47
Return for Revision	2013-12-27 13:49
Revised	2014-01-22 20:28
Second Decision	2014-04-29 12:24
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-04-29 14:19
Articles in Press	2014-05-23 11:00
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-05-08 15:59
Typeset the Manuscript	2014-08-30 14:00
Publish the Manuscript Online	2014-09-18 19:50

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Prospective Study
Article Title	Smoking increases the risk of extraintestinal manifestations in CD
Manuscript Source	Invited Manuscript
All Author List	Claudia Ott, Angela Takses, Florian Obermeier, Elisabeth Schnoy and Martina Müller
Funding Agency and Grant Number
Corresponding Author	Claudia Ott, MD, Department of Internal Medicine I, University of Regensburg, Franz-Josef-Strauss-Allee 11, 93042 Regensburg, Germany. claudia.ott@ukr.de
Key Words	Extraintestinal manifestations; CD; Ulcerative colitis; Smoking; Surgery; Age at onset
Core Tip	Owing to the high prevalence of extraintestinal manifestations (EIM) in patients with inflammatory bowel disease (IBD), CD and ulcerative colitis have to be considered as systemic diseases. However, prospective data on the prevalence of EIM at first diagnosis from population-based cohorts are lacking. We found a high prevalence of EIMs in our population-based cohort of IBD patients at first diagnosis, with an increased risk in patients with CD. More than 60% of patients developed an EIM during the early course of disease. Smoking, young age at disease onset and the need for IBD-related surgery were identified as risk factors for developing an EIM in CD.
Publish Date	2014-09-18 19:50
Citation	Ott C, Takses A, Obermeier F, Schnoy E, Müller M. Smoking increases the risk of extraintestinal manifestations in CD. World J Gastroenterol 2014; 20(34): 12269-12276
URL	http://www.wjgnet.com/1007-9327/full/v20/i34/12269.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i34.12269

Full Article (PDF)	WJG-20-12269.pdf
Full Article (Word)	WJG-20-12269.doc
Manuscript File	7320-Review.doc
Answering Reviewers	7320-Answering reviewers.pdf
Copyright License Agreement	7320-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	7320-Language certificate.pdf
Peer-review Report	7320-Peer reviews.pdf
Scientific Editor Work List	7320-Scientific editor work list.pdf