Publication Name	World Journal of Gastroenterology
Manuscript ID	73485
Country	Ireland

Received	2021-12-03 21:31
Peer-Review Started	2021-12-03 21:33
To Make the First Decision
Return for Revision	2022-01-27 08:06
Revised	2022-02-19 13:39
Second Decision	2022-04-26 02:19
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-04-26 20:54
Articles in Press	2022-04-26 20:54
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-05-30 01:37
Publish the Manuscript Online	2022-06-02 12:11

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Surgery
Manuscript Type	Basic Study
Article Title	Impact of radiotherapy on the immune landscape in oesophageal adenocarcinoma
Manuscript Source	Invited Manuscript
All Author List	Noel E Donlon, Maria Davern, Fiona O'Connell, Andrew Sheppard, Aisling Heeran, Anshul Bhardwaj, Christine Butler, Ravi Narayanasamy, Claire Donohoe, James J Phelan, Niamh Lynam-Lennon, Margaret R Dunne, Stephen Maher, Jacintha O'Sullivan, John V Reynolds and Joanne Lysaght
ORCID	Author(s) ORCID Number Noel E Donlon http://orcid.org/0000-0002-4073-3896 Maria Davern http://orcid.org/0000-0003-2278-5497 Fiona O'Connell http://orcid.org/0000-0002-3641-4374 Andrew Sheppard http://orcid.org/0000-0002-5973-7192 Aisling Heeran http://orcid.org/0000-0002-7209-155 Anshul Bhardwaj http://orcid.org/0000-0003-4421-8987 Christine Butler http://orcid.org/0000-0002-1597-5551 Ravi Narayanasamy http://orcid.org/0000-0001-9794-622 Claire Donohoe http://orcid.org/0000-0001-9373-2662 James J Phelan http://orcid.org/0000-0001-9431-2002 Niamh Lynam-Lennon http://orcid.org/0000-0001-8659-4943 Margaret R Dunne http://orcid.org/0000-0002-2816-5064 Stephen Maher http://orcid.org/0000-0003-0126-7906 Jacintha O'Sullivan http://orcid.org/0000-0001-8622-9858 John V Reynolds http://orcid.org/0000-0002-5501-9521 Joanne Lysaght http://orcid.org/0000-0003-3363-3763
Funding Agency and Grant Number
Corresponding Author	Noel E Donlon, MD, Assistant Professor, Department of Surgery, Trinity Translational Medicine Institute, St James Hospital, James’s Street, Dublin D08, Ireland. donlonn@tcd.ie
Key Words	Oeseophageal Cancer; Radiotherapy; Immunotherapy; Immunology; Surgery; Oncology
Core Tip	This body of work evaluates the impact of radiotherapy on the immune profile in oesophageal adenocarcinoma with an added caveat of immunotherapy effects on tumor cell killing.
Publish Date	2022-06-02 12:11
Citation	Donlon NE, Davern M, O’Connell F, Sheppard A, Heeran A, Bhardwaj A, Butler C, Narayanasamy R, Donohoe C, Phelan JJ, Lynam-Lennon N, Dunne MR, Maher S, O’Sullivan J, Reynolds JV, Lysaght J. Impact of radiotherapy on the immune landscape in oesophageal adenocarcinoma. World J Gastroenterol 2022; 28(21): 2302-2319
URL	https://www.wjgnet.com/1007-9327/full/v28/i21/2302.htm
DOI	https://dx.doi.org/10.3748/wjg.v28.i21.2302

Full Article (PDF)	WJG-28-2302.pdf
Full Article (Word)	WJG-28-2302.docx
Manuscript File	73485_Auto_Edited.docx
Answering Reviewers	73485-Answering reviewers.pdf
Audio Core Tip	73485-Audio core tip.m4a
Biostatistics Review Certificate	73485-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	73485-Conflict-of-interest statement.pdf
Copyright License Agreement	73485-Copyright license agreement.pdf
Institutional Review Board Approval Form or Document	73485-Institutional review board statement.pdf
Supplementary Material	73485-Supplementary material.pdf
Peer-review Report	73485-Peer-review(s).pdf
Scientific Misconduct Check	73485-Bing-Chen YL-2.png
Scientific Editor Work List	73485-Scientific editor work list.pdf
CrossCheck Report	73485-CrossCheck report.pdf