| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Reevaluation of the expanded indications in undifferentiated early gastric cancer for endoscopic submucosal dissection
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jiyoung Yoon, Seung-Yeon Yoo, Young Soo Park, Kee Don Choi, Beom Su Kim, Moon-Won Yoo, In Seob Lee, Jeong Hwan Yook, Ga Hee Kim, Hee Kyong Na, Ji Yong Ahn, Jeong Hoon Lee, Kee Wook Jung, Do Hoon Kim, Ho June Song, Gin Hyug Lee and Hwoon-Yong Jung |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Kee Don Choi, MD, PhD, Doctor, Doctor, Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, South Korea. keedon@amc.seoul.kr |
| Key Words |
Gastric cancer; Undifferentiated carcinoma; Endoscopic submucosal dissection; Lymph node metastasis |
| Core Tip |
This was a retrospective study investigating the prevalence and risk factors of lymph node metastasis (LNM) in cases with undifferentiated early gastric cancer meeting the expanded indication for endoscopic submucosal dissection (ESD). We found that the incidence rate of LNM was 1.1% (14/1240), which was higher than expected for indicated ESD. A subsequent case-control study revealed that two histological features-histologic purity of tumors and blurring of the muscularis mucosae underneath the tumorous epithelium-are promising factors for predicting the risk of LNM. Combining these histologic features could improve the current expanded indication criteria for ESD. |
| Publish Date |
2022-04-15 08:25 |
| Citation |
Yoon J, Yoo SY, Park YS, Choi KD, Kim BS, Yoo MW, Lee IS, Yook JH, Kim GH, Na HK, Ahn JY, Lee JH, Jung KW, Kim DH, Song HJ, Lee GH, Jung HY. Reevaluation of the expanded indications in undifferentiated early gastric cancer for endoscopic submucosal dissection. World J Gastroenterol 2022; 28(15): 1548-1562 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i15/1548.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i15.1548 |
