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Articles Published Processes
4/8/2022 12:06:56 PM | Browse: 391 | Download: 894
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Received |
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2021-12-06 03:38 |
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Peer-Review Started |
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2021-12-06 03:39 |
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To Make the First Decision |
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Return for Revision |
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2022-01-25 09:34 |
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Revised |
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2022-02-03 09:51 |
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Second Decision |
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2022-02-24 06:10 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-02-27 19:07 |
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Articles in Press |
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2022-02-27 19:07 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-03-27 11:50 |
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Publish the Manuscript Online |
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2022-04-08 12:06 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Hematology |
| Manuscript Type |
Case Report |
| Article Title |
Del(5q) and inv(3) in myelodysplastic syndrome: A rare case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hai-Ping Liang, Xing-Chun Luo, Ya-Li Zhang and Bei Liu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Bei Liu, MD, PhD, Professor, Department of Hematology, The First Affiliated Hospital, Lanzhou University, No. 1 Donggangxi Road, Chengguan District, Lanzhou 730000, Gansu Province, China. liubeiff@163.com |
| Key Words |
Myelodysplastic syndrome; Del(5q); Inv(3); Lenalidomide; Azacitidine; Case report |
| Core Tip |
We report a rare case of myelodysplastic syndrome (MDS) with two chromosomal structural abnormalities, del(5q) and inv(3). The patient evolved from the initial del(5q) to inv(3) combined with del(5q). Considering the deletion of chromosome 5q, we first treated the patient with lenalidomide. When drug resistance arose, we tried azacitidine, and the patient had a short remission. Finally, the patient refused treatment with haematopoietic stem cell transplantation (HSCT), and her condition gradually deteriorated until she was discharged from the hospital. In this rare and contradictory situation, we found that MDS patients with coexisting del(5q) and inv(3) may have a poor prognosis. However, azacitidine may play a role to some extent in MDS with del(5q) and inv(3), and HSCT may be the only way to cure the disease. |
| Publish Date |
2022-04-08 12:06 |
| Citation |
Liang HP, Luo XC, Zhang YL, Liu B. Del(5q) and inv(3) in myelodysplastic syndrome: A rare case report. World J Clin Cases 2022; 10(11): 3601-3608 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i11/3601.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i11.3601 |
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