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Articles Published Processes
7/13/2022 7:30:59 AM | Browse: 399 | Download: 1179
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Received |
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2021-12-21 13:33 |
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Peer-Review Started |
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2021-12-21 13:35 |
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To Make the First Decision |
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Return for Revision |
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2022-03-10 07:44 |
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Revised |
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2022-04-29 16:57 |
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Second Decision |
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2022-06-13 03:14 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-06-20 15:54 |
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Articles in Press |
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2022-06-20 15:54 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-06-07 20:51 |
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Typeset the Manuscript |
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2022-06-22 06:17 |
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Publish the Manuscript Online |
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2022-07-13 07:30 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Review |
| Article Title |
Tumor microenvironment involvement in colorectal cancer progression via Wnt/β-catenin pathway: Providing understanding of the complex mechanism of chemoresistance
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| Manuscript Source |
Invited Manuscript |
| All Author List |
María Belén Novoa Díaz, María Julia Martín and Claudia Gentili |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Agencia Nacional de Promoción Científica y Tecnológica |
PICT-2013-1441 |
| Consejo Nacional de Investigaciones Científicas y Técnicas |
PIP11220150100350 |
| Instituto Nacional del Cáncer Asistencia Financiera II, RESOL 493/14 |
2002-4395-14-1 |
| Instituto Nacional del Cáncer Asistencia Financiera III-2016-2017, RESOL-2016-1006-E-APN-MS |
2002-3862-16-1 |
| Universidad Nacional del Sur (PGI), Argentina |
24/B230 |
| Universidad Nacional del Sur (PGI), Argentina |
24/B303 |
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| Corresponding Author |
María Julia Martín, PhD, Research Assistant, Departamento de Biología, Bioquímica y Farmacia, Universidad Nacional del Sur (UNS)-INBIOSUR (CONICET-UNS), San Juan 670, Bahía Blanca 8000, Argentina. julia.martin@uns.edu.ar |
| Key Words |
Colorectal cancer; β-catenin pathway; Tumor stroma; Tumor microenvironment factors; Cancer progression; Drug resistance |
| Core Tip |
Currently, there is a high probability of failure in treatments of advanced stages of colorectal cancer (CRC). For this reason, it is necessary to provide a better understanding of CRC biology in a more global context for the future design of novel therapeutic approaches. The importance of the Wnt/β-catenin signaling pathway and the tumor microenvironment (TME) influence on the progression and chemoresistance of this disease were separately described in several review articles. Therefore, herein we comprehensively analyze the complex mechanisms of CRC chemoresistance triggered by TME factors that impact Wnt/β-catenin signaling. |
| Publish Date |
2022-07-13 07:30 |
| Citation |
Novoa Díaz MB, Martín MJ, Gentili C. Tumor microenvironment involvement in colorectal cancer progression via Wnt/β-catenin pathway: Providing understanding of the complex mechanism of chemoresistance. World J Gastroenterol 2022; 28(26): 3027-3046 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i26/3027.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i26.3027 |
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