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Articles Published Processes
8/12/2022 11:48:45 AM | Browse: 430 | Download: 908
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Received |
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2021-12-15 00:53 |
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Peer-Review Started |
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2021-12-15 00:55 |
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To Make the First Decision |
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Return for Revision |
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2022-01-12 00:44 |
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Revised |
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2022-01-24 16:51 |
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Second Decision |
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2022-07-13 02:49 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-07-18 00:05 |
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Articles in Press |
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2022-07-18 00:05 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-06-03 22:06 |
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Typeset the Manuscript |
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2022-08-07 14:15 |
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Publish the Manuscript Online |
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2022-08-12 11:48 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Basic Study |
| Article Title |
Improved systemic half-life of glucagon-like peptide-1-loaded carbonate apatite nanoparticles in rats
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Nabilah Ibnat, Rahela Zaman, Mohammad Borhan Uddin, Ezharul Chowdhury and Chooi Yeng Lee |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| FRGS grant from the Ministry of Education, Malaysia |
FRGS/2/2014/SG05/MUSM/03/1 |
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| Corresponding Author |
Chooi Yeng Lee, PhD, Senior Lecturer, School of Pharmacy, Monash University Malaysia, Jalan Lagoon Selatan, Subang Jaya 47500, Selangor, Malaysia. chooi.yeng.lee@monash.edu |
| Key Words |
Glucagon-like peptide-1; Metabolic syndrome; Nanoparticles; Plasma half-life; Rat |
| Core Tip |
Glucagon-like peptide-1 (GLP1), owing to its physiological properties, is a promising peptide in the treatment of obesity and diabetes. Due to the short half-life of GLP1 and in order to improve GLP1 therapeutic use, GLP1 receptor agonists (GLP1-RAs) have been widely synthesised and encapsulated into nanocarriers for targeted delivery. But the use of GLP1-RAs is associated with unwanted side effects and risks. In the present study, we synthesised a new nanocarrier for native GLP1 - the GLP1 carbonate apatite nanoparticles. The nanocarrier appears comparable if not significantly better than other GLP1 nanoparticles, which have shown promising features as therapeutic agents. |
| Publish Date |
2022-08-12 11:48 |
| Citation |
Ibnat N, Zaman R, Uddin MB, Chowdhury E, Lee CY. Improved systemic half-life of glucagon-like peptide-1-loaded carbonate apatite nanoparticles in rats. World J Diabetes 2022; 13(8): 613-621 |
| URL |
https://www.wjgnet.com/1948-9358/full/v13/i8/613.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v13.i8.613 |
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