Publication Name	World Journal of Gastroenterology
Manuscript ID	74199
Country	Sweden

Received	2021-12-16 14:44
Peer-Review Started	2021-12-16 14:46
To Make the First Decision
Return for Revision	2022-01-27 06:56
Revised	2022-02-01 11:09
Second Decision	2022-04-08 02:16
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-04-09 19:03
Articles in Press	2022-04-09 19:03
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-04-05 14:41
Typeset the Manuscript	2022-04-18 01:58
Publish the Manuscript Online	2022-05-17 12:57

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Letter to the Editor
Article Title	Effects of diabetes type 2 and metformin treatment in Swedish patients with colorectal cancer
Manuscript Source	Unsolicited Manuscript
All Author List	Jan Dimberg, Levar Shamoun, Kalle Landerholm and Dick Wågsäter
ORCID	Author(s) ORCID Number Jan Dimberg http://orcid.org/0000-0003-2328-7334 Levar Shamoun http://orcid.org/0000-0003-3519-7491 Kalle Landerholm http://orcid.org/0000-0001-6808-371X Dick Wågsäter http://orcid.org/0000-0002-3655-2419
Funding Agency and Grant Number	Funding Agency Grant Number Medical Research Council of Southeast Sweden FORSS-931897 Division of Medical Diagnostics of Region Jönköping County Futurum-970572
Corresponding Author	Dick Wågsäter, PhD, Professor, Department of Medical Cell Biology, Uppsala University, D1:3, Husargatan 3, Uppsala 751 23, Sweden. dick.wagsater@mcb.uu.se
Key Words	Diabetes; Metformin; Cytokines; Survival; Colorectal cancer; Polymorphism
Core Tip	Type 2 diabetes mellitus (DM) or metformin treatment does not influence mortality in colorectal cancer (CRC). Type 2 DM or metformin does not influence the levels of inflammatory factors in plasma in patients with CRC. Single nucleotide polymorphisms of insulin-like growth factor binding protein 7 are associated with type 2 DM in patients with CRC.
Publish Date	2022-05-17 12:57
Citation	Dimberg J, Shamoun L, Landerholm K, Wågsäter D. Effects of diabetes type 2 and metformin treatment in Swedish patients with colorectal cancer. World J Gastroenterol 2022; 28(19): 2148-2151
URL	https://www.wjgnet.com/1007-9327/full/v28/i19/2148.htm
DOI	https://dx.doi.org/10.3748/wjg.v28.i19.2148

Full Article (PDF)	WJG-28-2148.pdf
Full Article (Word)	WJG-28-2148.docx
Manuscript File	74199_Auto_Edited-YLC-Wang TQ.docx
Answering Reviewers	74199-Answering reviewers.pdf
Audio Core Tip	74199-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	74199-Conflict-of-interest statement.pdf
Copyright License Agreement	74199-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	74199-Language certificate.pdf
Peer-review Report	74199-Peer-review(s).pdf
Scientific Misconduct Check	74199-Bing-Chen YL-2.png
Scientific Editor Work List	74199-Scientific editor work list.pdf
CrossCheck Report	74199-CrossCheck report.pdf