Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	74218
Country	Japan

Received	2021-12-17 08:12
Peer-Review Started	2021-12-17 08:14
To Make the First Decision
Return for Revision	2022-01-27 10:41
Revised	2022-02-02 09:40
Second Decision	2022-03-08 03:19
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-03-17 05:17
Articles in Press	2022-03-17 05:17
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-02-27 23:02
Typeset the Manuscript	2022-04-01 11:15
Publish the Manuscript Online	2022-04-15 09:40

ISSN	1948-5204 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Review
Article Title	Role of sirtuins in esophageal cancer: Current status and future prospects
Manuscript Source	Invited Manuscript
All Author List	Ryota Otsuka, Koichi Hayano and Hisahiro Matsubara
ORCID	Author(s) ORCID Number Ryota Otsuka http://orcid.org/0000-0001-7360-9069 Koichi Hayano http://orcid.org/0000-0003-4733-8220 Hisahiro Matsubara http://orcid.org/0000-0002-2335-4704
Funding Agency and Grant Number
Corresponding Author	Koichi Hayano, FACS, MD, PhD, Associate Professor, Department of Frontier Surgery, Graduate School of Medicine, Chiba University, 1-8-1, Inohana, Chuo-ku, Chiba 260-8670, Japan. hayatin1973@gmail.com
Key Words	Esophageal cancer; Sirtuin; Esophageal squamous cell carcinoma; Esophageal adenocarcinoma; Biomarker; Treatment
Core Tip	Although there have been several reports on the function of sirtuins in cancer progression, the biological roles and clinical implications of sirtuins in esophageal cancer (EC) remain controversial. This is the first review to focus on sirtuins in the field of EC. In this review, we will briefly summarize the role of sirtuins in cancer and discuss the current findings and future prospects of sirtuins in EC.
Publish Date	2022-04-15 09:40
Citation	Otsuka R, Hayano K, Matsubara H. Role of sirtuins in esophageal cancer: Current status and future prospects. World J Gastrointest Oncol 2022; 14(4): 794-807
URL	https://www.wjgnet.com/1948-5204/full/v14/i4/794.htm
DOI	https://dx.doi.org/10.4251/wjgo.v14.i4.794

Full Article (PDF)	WJGO-14-794.pdf
Full Article (Word)	WJGO-14-794.docx
Manuscript File	74218_Auto_Edited-ZMG-FilipodiaCL.docx
Answering Reviewers	74218-Answering reviewers.pdf
Audio Core Tip	74218-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	74218-Conflict-of-interest statement.pdf
Copyright License Agreement	74218-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	74218-Language certificate.pdf
Peer-review Report	74218-Peer-review(s).pdf
Scientific Misconduct Check	74218-CrossCheck.jpg
Scientific Editor Work List	74218-Scientific editor work list.pdf
CrossCheck Report	74218-CrossCheck report.pdf