Publication Name	World Journal of Gastroenterology
Manuscript ID	7429
Country	China

Received	2013-11-18 09:06
Peer-Review Started	2013-11-18 12:17
First Decision by Editorial Office Director
Return for Revision	2013-12-26 16:31
Revised
Publication Fee Transferred
Second Decision by Editor	2014-04-23 09:14
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-04-23 10:14
Articles in Press	2014-05-23 09:23
Edit the Manuscript by Language Editor	2014-05-05 18:11
Typeset the Manuscript	2014-07-08 09:31
Publish the Manuscript Online	2014-07-21 17:17

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Prospective Study
Article Title	Hepatitis B surface antigen levels during natural history of chronic hepatitis B: A Chinese perspective study
Manuscript Source	Invited Manuscript
All Author List	Lin-Yan Zeng, Jiang-Shan Lian, Jian-Yang Chen, Hong-Yu Jia, Yi-Min Zhang, Dai-Rong Xiang, Liang Yu, Jian-Hua Hu, Ying-Feng Lu, Lin Zheng, Lan-Juan Li and Yi-Da Yang
Funding Agency and Grant Number	Funding Agency Grant Number National Key Program for Infectious Diseases of China 2013ZX10002001 (to Yang YD) 2th Five-Year Significant New Drugs Creation Plan of the Ministry of Science and Technology of China 2011ZX09302-003-03 (to Li LJ)
Corresponding Author	Yi-Da Yang, Professor, State Key Laboratory for Diagnosis and Treatment of Infectious Disease, the First Affiliated Hospital of Zhejiang University School of Medicine, 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. yangyida65@163.com
Key Words	Hepatitis B surface antigen quantification; Chronic hepatitis B; Natural history; Perspective
Core Tip	The quantification of serum hepatitis B surface antigen (HBsAg) has been recently advocated as a favorable marker of disease activity in chronic hepatitis B (CHB). Knowledge of HBsAg in the natural history of chronic hepatitis B is important for the management of the disease, but there is a lack of corresponding data on the base level of HBsAg in the natural history of CHB in China. Hence, the aim of this cross-sectional study was to evaluate the levels of HBsAg in consecutive phases of the natural history of hepatitis B virus-infection without the influence of antiviral treatment before, including the patients’ progression to liver cirrhosis.
Publish Date	2014-07-21 17:17
Citation	Zeng LY, Lian JS, Chen JY, Jia HY, Zhang YM, Xiang DR, Yu L, Hu JH, Lu YF, Zheng L, Li LJ, Yang YD. Hepatitis B surface antigen levels during natural history of chronic hepatitis B: A Chinese perspective study. World J Gastroenterol 2014; 20(27): 9178-9184
URL	http://www.wjgnet.com/1007-9327/full/v20/i27/9178.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i27.9178

Full Article (PDF)	WJG-20-9178.pdf
Full Article (Word)	WJG-20-9178.doc
Manuscript File	7429-Review.doc
Answering Reviewers	7429-Answering reviewers.pdf
Copyright License Agreement	7429-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	7429-Language certificate.pdf
Peer-review Report	7429-Peer reviews.pdf
Scientific Editor Work List	7429-Scientific editor work list.doc