| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Prospective Study |
| Article Title |
Hepatitis B surface antigen levels during natural history of chronic hepatitis B: A Chinese perspective study
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Lin-Yan Zeng, Jiang-Shan Lian, Jian-Yang Chen, Hong-Yu Jia, Yi-Min Zhang, Dai-Rong Xiang, Liang Yu, Jian-Hua Hu, Ying-Feng Lu, Lin Zheng, Lan-Juan Li and Yi-Da Yang |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Key Program for Infectious Diseases of China |
2013ZX10002001 (to Yang YD) |
| 2th Five-Year Significant New Drugs Creation Plan of the Ministry of Science and Technology of China |
2011ZX09302-003-03 (to Li LJ) |
|
| Corresponding Author |
Yi-Da Yang, Professor, State Key Laboratory for Diagnosis and Treatment of Infectious Disease, the First Affiliated Hospital of Zhejiang University School of Medicine, 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. yangyida65@163.com |
| Key Words |
Hepatitis B surface antigen quantification; Chronic hepatitis B; Natural history; Perspective |
| Core Tip |
The quantification of serum hepatitis B surface antigen (HBsAg) has been recently advocated as a favorable marker of disease activity in chronic hepatitis B (CHB). Knowledge of HBsAg in the natural history of chronic hepatitis B is important for the management of the disease, but there is a lack of corresponding data on the base level of HBsAg in the natural history of CHB in China. Hence, the aim of this cross-sectional study was to evaluate the levels of HBsAg in consecutive phases of the natural history of hepatitis B virus-infection without the influence of antiviral treatment before, including the patients’ progression to liver cirrhosis. |
| Publish Date |
2014-07-21 17:17 |
| Citation |
Zeng LY, Lian JS, Chen JY, Jia HY, Zhang YM, Xiang DR, Yu L, Hu JH, Lu YF, Zheng L, Li LJ, Yang YD. Hepatitis B surface antigen levels during natural history of chronic hepatitis B: A Chinese perspective study. World J Gastroenterol 2014; 20(27): 9178-9184 |
| URL |
http://www.wjgnet.com/1007-9327/full/v20/i27/9178.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v20.i27.9178 |
