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Articles Published Processes
7/11/2022 8:36:00 AM | Browse: 286 | Download: 707
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Received |
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2021-12-24 02:41 |
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Peer-Review Started |
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2021-12-24 02:43 |
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To Make the First Decision |
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Return for Revision |
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2022-02-14 08:57 |
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Revised |
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2022-02-21 05:22 |
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Second Decision |
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2022-05-30 02:49 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-06-03 21:18 |
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Articles in Press |
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2022-06-03 21:18 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-05-23 13:56 |
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Typeset the Manuscript |
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2022-07-02 10:43 |
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Publish the Manuscript Online |
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2022-07-11 08:36 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Immunology |
| Manuscript Type |
Opinion Review |
| Article Title |
Effects of glucocorticoids on leukocyte: Genomic and non-genomic mechanisms
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Wan-Yu Jia and Jian-Jiang Zhang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Provinces Co-construction Program of Medical Science and Technique Foundation of Henan Province |
SB201901042 |
| Key Scientific Research Project of Colleges and Universities in Henan Province |
21A320070 |
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| Corresponding Author |
Jian-Jiang Zhang, Doctor, MD, PhD, Chief Physician, Department of Pediatrics, the First Affiliated Hospital of Zhengzhou University, No. 1 Jianshe East Road, Erqi District, Zhengzhou 450052, Henan Province, China. zhangjianjiang1@hotmail.com |
| Key Words |
Glucocorticoid; Leukocyte; Count; Functions; Glucocorticoid receptor |
| Core Tip |
Glucocorticoids (GCs) increase peripheral blood neutrophil counts through genomic and nongenomic actions and reduce the numbers of lymphocytes, eosinophils, basophils, and monocytes. GCs also regulate cell activity and affect cells. The functions of adhesion, activation, secretion and differentiation inhibit the expression of proinflammatory factors and chemokines. The mechanisms of action of GCs include effects on intracellular transcription and protein expression, effects on mitochondria, physical and chemical interactions with biological membranes, and receptor-mediated interactions with signal proteins. |
| Publish Date |
2022-07-11 08:36 |
| Citation |
Jia WY, Zhang JJ. Effects of glucocorticoids on leukocytes: Genomic and non-genomic mechanisms. World J Clin Cases 2022; 10(21): 7187-7194 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i21/7187.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i21.7187 |
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