Publication Name	World Journal of Gastroenterology
Manuscript ID	7448
Country	Iran

Received	2013-11-19 14:28
Peer-Review Started	2013-11-19 20:23
First Decision by Editorial Office Director
Return for Revision	2013-12-25 14:47
Revised
Publication Fee Transferred
Second Decision by Editor	2014-04-29 12:54
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2014-04-29 14:13
Articles in Press	2014-05-23 09:52
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-06-12 09:37
Publish the Manuscript Online	2014-07-03 15:30

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Non-alcoholic fatty liver disease and thyroid dysfunction: A systematic review
Manuscript Source	Invited Manuscript
All Author List	Ahad Eshraghian and Alireza Hamidian Jahromi
Funding Agency and Grant Number
Corresponding Author	Ahad Eshraghian, MD, Department of Internal Medicine, Namazi hospital, Shiraz University of medical sciences, PO Box 71345-1744 Shiraz, Iran. eshraghiana@yahoo.com
Key Words	Non alcoholic fatty liver disease; Thyroid dysfunction; Hypothyroidism; Non alcoholic steatohepatitis; Risk factor; Pathophysiology
Core Tip	Thyroid hormones help regulate of body weight, lipid metabolism, and insulin resistance. Therefore, thyroid hormones may have a role in the pathogenesis of non alcoholic fatty liver disease (NAFLD) and non alcoholic steatohepatitis (NASH). Following a systematic review of human studies in the English language medical literature, eleven articles were found to address this relationship. Hypothyroidism appears to be an independent risk factor for NAFLD/NASH in some studies; however, other studies failed to find such an association. As the results of these studies are not consistent, further research is recommended to determine the relationship hypothyroidism and NAFLD/NASH and the underlying mechanisms.
Publish Date	2014-07-03 15:30
Citation	Eshraghian A, Hamidian Jahromi A. Non-alcoholic fatty liver disease and thyroid dysfunction: A systematic review. World J Gastroenterol 2014; 20(25): 8102-8109
URL	http://www.wjgnet.com/1007-9327/full/v20/i25/8102.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i25.8102

Full Article (PDF)	WJG-20-8102.pdf
Full Article (Word)	WJG-20-8102.doc
Manuscript File	7448-Review.doc
Biostatistics Review Certificate	Biostatistician_Review_Report_20131119043347.docx