Publication Name	World Journal of Gastroenterology
Manuscript ID	7449
Country	Japan

Received	2013-11-19 14:30
Peer-Review Started	2013-11-19 20:37
To Make the First Decision	2014-01-09 16:46
Return for Revision	2014-01-12 17:46
Revised	2014-02-10 07:12
Second Decision	2014-03-10 13:29
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-03-10 17:20
Articles in Press	2014-05-23 11:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-06-24 13:48
Publish the Manuscript Online	2014-07-14 17:39

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Two-stage treatment with hepatectomy and carbon-ion radiotherapy for multiple hepatic epithelioid hemangioendotheliomas
Manuscript Source	Invited Manuscript
All Author List	Shohei Komatsu, Takeshi Iwasaki, Yusuke Demizu, Kazuki Terashima, Osamu Fujii, Atsushi Takebe, Akihiro Toyokawa, Kazuhiro Teramura, Takumi Fukumoto, Yonson Ku and Nobukazu Fuwa
Funding Agency and Grant Number
Corresponding Author	Shohei Komatsu, MD, PhD, Division of Hepato-Biliary-Pancreatic Surgery, Department of Surgery, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Hyogo 650-0017, Japan. komasho8@gmail.com
Key Words	Two-stage treatment; Hepatic epithelioid hemangioendothelioma; Hepatectomy; Carbon-ion radiotherapy; Particle radiotherapy; Omental flap spacer
Core Tip	Hepatic epithelioid hemangioendothelioma (HEH) is a rare neoplasm with variable malignant potential. Liver transplantation is the most frequently reported treatment because most patients have multifocal bilobar lesions. Here, we describe a case of a 35-year-old woman with unresectable multiple bilobar HEH that was successfully treated by combination treatment of hepatectomy and carbon-ion radiotherapy. This case demonstrated two significant points: the effectiveness of carbon-ion radiotherapy for HEH and the possibility of expanding the curative treatment options for multiple bilobar hepatic tumors.
Publish Date	2014-07-14 17:39
Citation	Komatsu S, Iwasaki T, Demizu Y, Terashima K, Fujii O, Takebe A, Toyokawa A, Teramura K, Fukumoto T, Ku Y, Fuwa N. Two-stage treatment with hepatectomy and carbon-ion radiotherapy for multiple hepatic epithelioid hemangioendotheliomas. World J Gastroenterol 2014; 20(26): 8729-8735
URL	http://www.wjgnet.com/1007-9327/full/v20/i26/8729.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i26.8729

Full Article (PDF)	WJG-20-8729.pdf
Full Article (Word)	WJG-20-8729.doc
Manuscript File	7449-Review.doc
Answering Reviewers	7449-Answering reviewers.pdf
Copyright License Agreement	7449-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	7449- Language certificate.pdf
Peer-review Report	7449-Peer review(s).pdf
Scientific Editor Work List	7449-Scientific editor work list.doc