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Articles Published Processes
7/5/2022 1:22:29 AM | Browse: 292 | Download: 769
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Received |
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2021-12-28 07:05 |
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Peer-Review Started |
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2021-12-28 07:06 |
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To Make the First Decision |
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Return for Revision |
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2022-01-23 12:02 |
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Revised |
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2022-02-02 14:37 |
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Second Decision |
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2022-04-15 02:03 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-04-15 16:49 |
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Articles in Press |
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2022-04-15 16:49 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-05-24 09:35 |
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Typeset the Manuscript |
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2022-06-24 06:57 |
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Publish the Manuscript Online |
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2022-07-05 01:22 |
ISSN |
2307-8960 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Pharmacology & Pharmacy |
Manuscript Type |
Systematic Reviews |
Article Title |
Network pharmacology-based strategy for predicting therapy targets of Sanqi and Huangjing on diabetes mellitus
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Xiao-Yan Cui, Xiao Wu, Dan Lu and Dan Wang |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Dan Wang, PhD, Teacher, College of Human Kinesiology, Shenyang Sport University, No. 36 Jinqiansong East Road Sujiatun District, Shenyang 110102, Liaoning Province, China. 595680903@qq.com |
Key Words |
Panax notoginseng (Sanqi in Chinese); Polygonati Rhizoma (Huangjing in Chinese); Diabetes mellitus; Active compounds; Network pharmacology; Hub genes |
Core Tip |
Due to the unsatisfactory therapeutic effects of monotherapy, combination therapy has become a preferable choice for diabetic patients. Two certain herbs are often used together for the treatment of some diseases, which is called as herb pair. Hence, we investigated the combined effects of Sanqi and Huangjing (SQHJ) on diabetes and the underlying molecular mechanisms. Network pharmacology is a new discipline based on the theory of systems biology, which analyzes the network of biological systems and selects specific signal nodes for multitarget drug molecular design 16. Therefore, we use the network pharmacology to reveal the pharmacological mechanism of SQHJ in the treatment of diabetes from three aspects of active components, potential targets, and synthetic pathways. |
Publish Date |
2022-07-05 01:22 |
Citation |
Cui XY, Wu X, Lu D, Wang D. Network pharmacology-based strategy for predicting therapy targets of Sanqi and Huangjing in diabetes mellitus. World J Clin Cases 2022; 10(20): 6900-6914 |
URL |
https://www.wjgnet.com/2307-8960/full/v10/i20/6900.htm |
DOI |
https://dx.doi.org/10.12998/wjcc.v10.i20.6900 |
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