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Articles Published Processes
9/1/2014 11:47:00 AM | Browse: 1409 | Download: 1235
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Received |
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2013-11-20 13:48 |
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Peer-Review Started |
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2013-11-20 15:10 |
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To Make the First Decision |
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2013-12-25 18:15 |
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Return for Revision |
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2013-12-27 20:51 |
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Revised |
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2013-12-28 19:57 |
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Second Decision |
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2014-01-20 08:50 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-01-20 09:57 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2014-02-27 15:13 |
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Typeset the Manuscript |
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2014-04-14 17:15 |
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Publish the Manuscript Online |
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2014-04-18 11:34 |
Category |
Endocrinology & Metabolism |
Manuscript Type |
Topic Highlights |
Article Title |
Recent advances in the molecular genetics of type 2 diabetes mellitus
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Manuscript Source |
Invited Manuscript |
All Author List |
Antonio Brunetti, Eusebio Chiefari and Daniela Foti |
Funding Agency and Grant Number |
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Corresponding Author |
Antonio Brunetti, MD, PhD, Professor, Department of Health Sciences, University “Magna Græcia” of Catanzaro, Viale Europa, Località Germaneto, 88100 Catanzaro, Italy. brunetti@unicz.it |
Key Words |
Genome-wide association study; Candidate gene; Genetic variants; High-mobility group A1; Insulin resistant diabetes |
Core Tip |
Despite the progress in clinical and laboratory investigations, the fundamental cause of type 2 diabetes mellitus (T2DM) remains uncertain. Candidate gene, linkage and genome-wide association studies have highlighted the role of genetics in the development of T2DM. Using these strategies, a large number of variants have been identified in many genes, most of which may influence an individual’s risk of developing T2DM. In this review, we compile information on genetic factors that influence the risk of T2DM. In addition, we discuss the results from recent studies on the role of HMGA1 on the issue, which might be important for future breakthroughs in this field. |
Publish Date |
2014-04-18 11:34 |
Citation |
Brunetti A, Chiefari E, Foti D. Recent advances in the molecular genetics of type 2 diabetes mellitus. World J Diabetes 2014; 5(2): 128-140 |
URL |
http://www.wjgnet.com/1948-9358/full/v5/i2/128.htm |
DOI |
http://dx.doi.org/10.4239/wjd.v5.i2.128 |
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