Publication Name	World Journal of Clinical Pediatrics
Manuscript ID	74604
Country	Pakistan

Received	2021-12-29 11:11
Peer-Review Started	2021-12-29 11:11
To Make the First Decision
Return for Revision	2022-03-16 08:52
Revised	2022-03-21 10:42
Second Decision	2022-05-30 02:47
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-06-03 21:45
Articles in Press	2022-06-03 21:45
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-05-09 22:50
Typeset the Manuscript	2022-06-14 08:32
Publish the Manuscript Online	2022-07-06 13:21

ISSN	2219-2808 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Pathology
Manuscript Type	Observational Study
Article Title	Children with lysinuric protein intolerance: Experience from a lower middle income country
Manuscript Source	Unsolicited Manuscript
All Author List	Syed Bilal Hashmi and Sibtain Ahmed
ORCID	Author(s) ORCID Number Syed Bilal Hashmi http://orcid.org/0000-0001-8813-4158 Sibtain Ahmed http://orcid.org/0000-0003-0316-2622
Funding Agency and Grant Number
Corresponding Author	Sibtain Ahmed, FCPS, MBBS, Assistant Professor, Department of Pathology and Laboratory Medicine, Aga Khan University Hospital, National Stadium Rd, Karachi 74800, Pakistan. sibtain.ahmed@aku.edu
Key Words	Lysinuric protein intolerance; Consanguinity; Pakistan; Retrospective study
Core Tip	Lysinuric protein intolerance is an inherited biochemical disorder with just over 140 individuals worldwide. In this disorder, there is defective absorption and excretion of dibasic amino acids, such as lysine, arginine and ornithine. This is the first study from Pakistan, which has a high prevalence of inherited metabolic disorders. Only 4 previously reported cases were identified from South Asia. This study shows the biochemical pattern and clinical characteristics in patients with a suggestive diagnosis of lysinuric protein intolerance on biochemical workup.
Publish Date	2022-07-06 13:21
Citation	Hashmi SB, Ahmed S. Children with lysinuric protein intolerance: Experience from a lower middle income country. World J Clin Pediatr 2022; 11(4): 369-374
URL	https://www.wjgnet.com/2219-2808/full/v11/i4/369.htm
DOI	https://dx.doi.org/10.5409/wjcp.v11.i4.369

Full Article (PDF)	WJCP-11-369.pdf
Full Article (Word)	WJCP-11-369.docx
Manuscript File	74604_Auto_Edited-HZ-FilipodiaCL-LS.docx
Answering Reviewers	74604-Answering reviewers.pdf
Audio Core Tip	74604-Audio core tip.mp3
Biostatistics Review Certificate	74604-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	74604-Conflict-of-interest statement.pdf
Copyright License Agreement	74604-Copyright license agreement.pdf
Institutional Review Board Approval Form or Document	74604-Institutional review board statement.pdf
Peer-review Report	74604-Peer-review(s).pdf
Scientific Editor Work List	74604-Scientific editor work list.pdf
CrossCheck Report	74604-CrossCheck report.pdf