Publication Name	World Journal of Stem Cells
Manuscript ID	74722
Country	Hungary

Received	2022-01-03 20:21
Peer-Review Started	2022-01-03 20:23
To Make the First Decision
Return for Revision	2022-03-13 22:37
Revised	2022-03-15 18:30
Second Decision	2022-05-24 03:18
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-05-28 07:20
Articles in Press	2022-05-28 07:20
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-05-20 11:35
Typeset the Manuscript	2022-06-21 00:49
Publish the Manuscript Online	2022-06-24 10:26

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Cell Biology
Manuscript Type	Field of Vision
Article Title	Disagreements in the therapeutic use of mesenchymal stem cell-derived secretome
Manuscript Source	Invited Manuscript
All Author List	Ferenc Sipos and Györgyi Műzes
ORCID	Author(s) ORCID Number Ferenc Sipos http://orcid.org/0000-0002-2767-7746 Györgyi Műzes http://orcid.org/0000-0002-9099-0372
Funding Agency and Grant Number	Funding Agency Grant Number Startup Program of Semmelweis University Faculty of Medicine SE10332470
Corresponding Author	Ferenc Sipos, MD, PhD, Senior Lecturer, Department of Internal Medicine and Hematology, Semmelweis University, Szentkirályi Street 46, Budapest 1088, Hungary. dr.siposf@gmail.com
Key Words	Mesenchymal stem cells; Secretome; Exosomes; Regeneration; Therapy; Cancer
Core Tip	The authors of a recent article provide a detailed summary of the properties and biological functions of mesenchymal stem cell (MSC)-derived exosomes, one of the most important fractions of the MSC-derived secretome. However, in addition to their undeniable benefits, there are a number of risks associated with their use. Exosomes have the potential to have a significant impact on the development of diseases such as cancer. The use of MSC-derived secretomes for therapeutic purposes must be approached with extreme caution.
Publish Date	2022-06-24 10:26
Citation	Sipos F, Műzes G. Disagreements in the therapeutic use of mesenchymal stem cell-derived secretome. World J Stem Cells 2022; 14(6): 365-371
URL	https://www.wjgnet.com/1948-0210/full/v14/i6/365.htm
DOI	https://dx.doi.org/10.4252/wjsc.v14.i6.365

Full Article (PDF)	WJSC-14-365.pdf
Full Article (Word)	WJSC-14-365.docx
Manuscript File	74722_Auto_Edited-JRF-Webster J-LS.docx
Answering Reviewers	74722-Answering reviewers.pdf
Audio Core Tip	74722-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	74722-Conflict-of-interest statement.pdf
Copyright License Agreement	74722-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	74722-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	74722-Language certificate.pdf
Peer-review Report	74722-Peer-review(s).pdf
Scientific Misconduct Check	74722-Bing-Fan JR-2.png
Scientific Editor Work List	74722-Scientific editor work list.pdf
CrossCheck Report	74722-CrossCheck report.pdf
CrossCheck Report	74722-CrossCheck.png