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Articles Published Processes
5/12/2022 8:42:29 AM | Browse: 339 | Download: 747
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Received |
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2022-01-07 12:46 |
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Peer-Review Started |
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2022-01-07 12:47 |
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To Make the First Decision |
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Return for Revision |
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2022-03-09 04:53 |
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Revised |
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2022-03-17 06:19 |
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Second Decision |
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2022-04-02 02:09 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-04-04 05:58 |
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Articles in Press |
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2022-04-04 05:58 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-04-24 06:49 |
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Publish the Manuscript Online |
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2022-05-12 08:42 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pharmacology & Pharmacy |
| Manuscript Type |
Minireviews |
| Article Title |
Targeting pancreatic cancer immune evasion by inhibiting histone deacetylases
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Wynne Sim, Wei-Meng Lim, Ling-Wei Hii, Chee-Onn Leong and Chun-Wai Mai |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| International Medical University to Sim W, Lim WM, and Leong CO |
BMS I/2020(10) |
| Shanghai Municipal Science and Technology Commission to Mai CW |
20WZ250460 |
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| Corresponding Author |
Chun-Wai Mai, BPharm, PhD, Postdoctoral Fellow, State Key Laboratory of Oncogenes and Related Genes, Renji-Med X Clinical Stem Cell Research Center, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 160 Pujian Road, Building No. 17, Pudong New District
, Shanghai 200127, China. mai.chunwai@outlook.com |
| Key Words |
Histone acetylation; Histone deacetylases inhibitors; Immune evasion; Pancreatic cancers; Pancreatic ductal adenocarcinoma |
| Core Tip |
There are several broad reviews covering histone deacetylases (HDAC) in cancer but none on its role in modulating immune evasion in pancreatic cancer. This is the first review to discuss the role of HDAC in the context of immune-evading pancreatic cancer. We also summarize the evidence of HDAC inhibitors in targeting immune-evading pancreatic cancer. This mini review also covers our perspective in the strategies to target overexpression of HDAC in pancreatic cancer. |
| Publish Date |
2022-05-12 08:42 |
| Citation |
Sim W, Lim WM, Hii LW, Leong CO, Mai CW. Targeting pancreatic cancer immune evasion by inhibiting histone deacetylases. World J Gastroenterol 2022; 28(18): 1934-1945 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i18/1934.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i18.1934 |
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