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5/24/2022 12:41:49 PM | Browse: 232 | Download: 325
Publication Name World Journal of Clinical Oncology
Manuscript ID 74768
Country/Territory Italy
Received
2022-01-05 18:04
Peer-Review Started
2022-01-05 18:06
To Make the First Decision
Return for Revision
2022-02-15 00:10
Revised
2022-04-01 09:13
Second Decision
2022-05-05 03:14
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2022-05-07 00:44
Articles in Press
2022-05-07 00:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
2022-05-03 00:07
Typeset the Manuscript
2022-05-13 08:19
Publish the Manuscript Online
2022-05-24 12:41
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Letter to the Editor
Article Title How to improve metastatic pancreatic ductal adenocarcinoma patients’ selection: Between clinical trials and the real-world
Manuscript Source Invited Manuscript
All Author List Andrea Pretta, Dario Spanu, Stefano Mariani, Nicole Liscia, Pina Ziranu, Valeria Pusceddu, Marco Puzzoni, Elena Massa, Mario Scartozzi and Eleonora Lai
ORCID
Author(s) ORCID Number
Andrea Pretta http://orcid.org/0000-0002-0262-9270
Dario Spanu http://orcid.org/0000-0003-2968-6811
Stefano Mariani http://orcid.org/0000-0002-2513-1408
Nicole Liscia http://orcid.org/0000-0002-0799-0209
Pina Ziranu http://orcid.org/0000-0002-5659-7366
Valeria Pusceddu http://orcid.org/0000-0003-4167-9091
Marco Puzzoni http://orcid.org/0000-0001-5880-4309
Mario Scartozzi http://orcid.org/0000-0001-5977-5546
Eleonora Lai http://orcid.org/0000-0002-0275-8187
Funding Agency and Grant Number
Corresponding Author Mario Scartozzi, MD, Chairman, Full Professor, Medical Oncology Unit, University Hospital and University of Cagliari, SS 554, bivio per Sestu, km 4,500, Monserrato 09042, Cagliari, Italy. marioscartozzi@gmail.com, Monserrato 09042, Cagliari, Italy. marioscartozzi@gmail.com
Key Words Metastatic pancreatic ductal adenocarcinoma; Palliative chemotherapy; Real-world data; Molecular selection; Biomarkers; Second-line treatment
Core Tip The present letter is intended to contribute to the collection of data on pancreatic ductal adenocarcinoma (PDAC) treatments in second-line settings through our experience with the promising data of efficacy and safety of a small group of study patients treated with second-line liposomal irinotecan (nal-IRI) plus 5-fluorouracil and leucovorin. We also focused on highlighting the subgroups of PDAC patients who might benefit from target treatments, such as a small proportion of mutated BRCAs, and to identify comorbidities or characteristics that impact the prognosis of PDAC patients through our retrospective analysis that demonstrate a correlation between type II diabetes mellitus and improved overall survival.
Publish Date 2022-05-24 12:41
Citation Pretta A, Spanu D, Mariani S, Liscia N, Ziranu P, Pusceddu V, Puzzoni M, Massa E, Scartozzi M, Lai E. How to improve metastatic pancreatic ductal adenocarcinoma patients’ selection: Between clinical trials and the real-world. World J Clin Oncol 2022; 13(5): 417-422
URL https://www.wjgnet.com/2218-4333/full/v13/i5/417.htm
DOI https://dx.doi.org/10.5306/wjco.v13.i5.417
Full Article (PDF) WJCO-13-417.pdf
Full Article (Word) WJCO-13-417.docx
Manuscript File 74768_Auto_Edited-YXJW-FilipodiaCL.docx
Answering Reviewers 74768-Answering reviewers.pdf
Audio Core Tip 74768-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 74768-Conflict-of-interest statement.pdf
Copyright License Agreement 74768-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 74768-Language certificate.pdf
Peer-review Report 74768-Peer-review(s).pdf
Scientific Misconduct Check 74768-Bing-Wu YXJ-2.png
Scientific Editor Work List 74768-Scientific editor work list.pdf