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Articles Published Processes
8/3/2022 7:54:39 AM | Browse: 367 | Download: 761
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Received |
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2022-01-14 15:42 |
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Peer-Review Started |
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2022-01-14 15:42 |
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To Make the First Decision |
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Return for Revision |
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2022-04-12 02:07 |
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Revised |
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2022-04-26 16:53 |
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Second Decision |
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2022-07-04 03:05 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-07-06 03:13 |
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Articles in Press |
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2022-07-06 03:13 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-07-01 01:17 |
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Typeset the Manuscript |
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2022-07-27 00:06 |
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Publish the Manuscript Online |
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2022-08-03 07:54 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Basic Study |
| Article Title |
N-linked glycoproteomic profiling in esophageal squamous cell carcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Qi-Wei Liu, Hao-Jie Ruan, Wei-Xia Chao, Meng-Xiang Li, Ye-Lin Jiao, Douglas G Ward, She-Gan Gao and Yi-Jun Qi |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81072039 |
| National Natural Science Foundation of China |
81872037 |
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| Corresponding Author |
Yi-Jun Qi, MD, PhD, Professor, Henan Key Laboratory of Microbiome and Esophageal Cancer Prevention and Treatment; Henan Key Laboratory of Cancer Epigenetics; Cancer Hospital, The First Affiliated Hospital, College of Clinical Medicine, Henan University of Science and Technology, No. 29 Jinghua Road, Luoyang 471003, Henan Province, China. qiyijun@haust.edu.cn |
| Key Words |
Esophageal squamous cell carcinoma; N-linked glycoprotein; Post-translational modification; Lectin; Cathepsin D; Haptoglobin; 14-3-3ζ |
| Core Tip |
Comprehensive N-linked glycoproteome was profiled by two-dimensional gel electrophoresis-based and isobaric tags for relative and absolute quantification (iTRAQ) labeling-based mass spectrometry quantitation in parallel after N-linked glycoprotein enrichment by a tandem of multilectin affinity chromatography. The iTRAQ labeling-based quantitative proteomic profiling outperformed protein spot intensity quantification used by two-dimensional gel electrophoresis. A total of 411 N-linked glycoproteins were identified, including 128 up-regulated and 283 down-regulated glycoproteins with differential expression, which provide the scientific community with a dataset of glycoproteins associated with esophageal squamous cell carcinoma for in-depth investigation. |
| Publish Date |
2022-08-03 07:54 |
| Citation |
Liu QW, Ruan HJ, Chao WX, Li MX, Jiao YL, Ward DG, Gao SG, Qi YJ. N-linked glycoproteomic profiling in esophageal squamous cell carcinoma. World J Gastroenterol 2022; 28(29): 3869-3885 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i29/3869.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i29.3869 |
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