Publication Name	World Journal of Gastroenterology
Manuscript ID	7482
Country	Italy

Received	2013-11-21 10:44
Peer-Review Started	2013-11-21 19:10
To Make the First Decision	2014-01-09 16:23
Return for Revision	2014-01-12 17:51
Revised
Second Decision	2014-03-19 13:57
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-03-19 14:58
Articles in Press	2014-05-23 11:21
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-06-02 14:40
Publish the Manuscript Online	2014-06-27 10:37

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Surgery
Manuscript Type	Topic Highlights
Article Title	Hepatocellular carcinoma: Surgical perspectives beyond the barcelona clinic liver cancer recommendations
Manuscript Source	Invited Manuscript
All Author List	Alfredo Guglielmi, Andrea Ruzzenente, Simone Conci, Alessandro Valdegamberi, Marco Vitali, Francesca Bertuzzo, Michela De Angelis, Guido Mantovani and Calogero Iacono
Funding Agency and Grant Number
Corresponding Author	Calogero Iacono, Professor, Department of Surgery, Division of General Surgery A, Unit of Hepato-Pancreatico-Biliary surgery, University of Verona Medical School, University Hospital “GB Rossi”, P.le L.A. Scuro, 37134 Verona, Italy. calogero.iacono@univr.it
Key Words	Hepatocellular carcinoma; Liver resection; Hepatectomy; Barcelona clinic liver cancer; Surgical therapy
Core Tip	The present review reports the results of surgery beyond the barcelona clinic liver cancer recommendations. Recent studies have reported that surgical resection can result in good short- and long-term survival in patients with early hepatocellular carcinoma (HCC) with portal hypertension and in patients with intermediate-advanced HCC. A careful preoperative evaluation, including liver function and remnant volume assessment, is mandatory before liver resection in HCC patients. An understanding of the biological behaviour of these tumours through molecular biology studies may be useful in choosing the optimal treatment strategy.
Publish Date	2014-06-27 10:37
Citation	Guglielmi A, Ruzzenente A, Conci S, Valdegamberi A, Vitali M, Bertuzzo F, De Angelis M, Mantovani G, Iacono C. Hepatocellular carcinoma: Surgical perspectives beyond the barcelona clinic liver cancer recommendations. World J Gastroenterol 2014; 20(24): 7525-7533
URL	http://www.wjgnet.com/1007-9327/full/v20/i24/7525.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i24.7525

Full Article (PDF)	WJG-20-7525.pdf
Full Article (Word)	WJG-20-7525.doc
Manuscript File	7482-Review.doc
Answering Reviewers	7482-Answering Reviewers.pdf
Copyright License Agreement	7482-Copyright Assignment.pdf
Non-Native Speakers of English Editing Certificate	7482-Language certificate.pdf
Peer-review Report	7482-Peer review(s).pdf
Scientific Editor Work List	7482-Scientific editor work list.doc