Publication Name	World Journal of Biological Chemistry
Manuscript ID	7485
Country	Germany

Received	2013-11-21 11:04
Peer-Review Started	2013-11-21 20:26
To Make the First Decision	2013-12-25 18:13
Return for Revision	2013-12-27 20:41
Revised	2013-12-29 00:25
Second Decision	2014-01-20 08:52
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-20 09:58
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-02-27 23:05
Typeset the Manuscript	2014-05-19 12:07
Publish the Manuscript Online	2014-06-11 10:30

ISSN	1949-8454 (online)
Open Access
Copyright
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Website	http://www.wjgnet.com

Category	Biology
Manuscript Type	Review
Article Title	Endoglin in liver fibrogenesis: Bridging basic science and clinical practice
Manuscript Source	Invited Manuscript
All Author List	Steffen K Meurer, Muhammad Alsamman, David Scholten and Ralf Weiskirchen
Funding Agency and Grant Number	Funding Agency Grant Number Deutsche Forschungsgemeinschaft SFB/TRR57 P13 Deutsche Forschungsgemeinschaft SFB/TRR57 P26 Interdisciplinary Centre for Clinical Research within the faculty of Medicine at the RWTH Aachen University IZKF Aachen, Project E6-11 to Weiskirchen R
Corresponding Author	Ralf Weiskirchen, Professor, Institute of Clinical Chemistry and Pathobiochemistry, RWTH University Hospital Aachen, Pauwelsstr 30, D-52074 Aachen, Germany. rweiskirchen@ukaachen.de
Key Words	Telangiectasia; Signalling; Transforming growth factor-β; Disease; Bleeding disorders
Core Tip	Endoglin is an accessory receptor for transforming growth factor-β impacting various aspects of its signaling and biological functions. Endoglin mutations are inherited as autosomal dominant disorders and may cause severe defects in different organs, including brain, lung and liver. In the present review, we will highlight the pathogenesis of several of these disorders and give an overview about the important role of endoglin dysfunction in the pathology of liver fibrosis.
Publish Date	2014-06-11 10:30
Citation	Meurer SK, Alsamman M, Scholten D, Weiskirchen R. Endoglin in liver fibrogenesis: Bridging basic science and clinical practice. World J Biol Chem 2014; 5(2): 180-203
URL	http://www.wjgnet.com/1949-8454/full/v5/i2/180.htm
DOI	http://dx.doi.org/10.4331/wjbc.v5.i2.180

Full Article (PDF)	wjbc-5-180.pdf
Full Article (Word)	wjbc-5-180.doc
Manuscript File	7585-Review.doc
Answering Reviewers	7485-Answering reviewers.pdf
Copyright License Agreement	7485-Copyright assignment.pdf
Peer-review Report	7485-Peer review(s).pdf
Scientific Editor Work List	7485-Scientific editor work list.doc