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Articles Published Processes
7/6/2022 1:21:32 PM | Browse: 402 | Download: 1143
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Received |
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2022-01-10 13:54 |
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Peer-Review Started |
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2022-01-10 13:57 |
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To Make the First Decision |
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Return for Revision |
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2022-03-08 21:58 |
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Revised |
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2022-03-11 13:36 |
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Second Decision |
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2022-05-30 02:47 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-06-03 21:44 |
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Articles in Press |
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2022-06-03 21:44 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-05-26 21:28 |
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Typeset the Manuscript |
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2022-06-14 08:45 |
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Publish the Manuscript Online |
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2022-07-06 13:21 |
| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Frequency of celiac disease and distribution of HLA-DQ2/DQ8 haplotypes among siblings of children with celiac disease
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Yasin Sahin and Serdar Mermer |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Yasin Sahin, MD, Associate Professor, Pediatric Gastroenterology, Mersin Training and Research Hospital, Korukent Mah. 96015 Sok. Mersin Entegre Sağlık Kampüsü 33240 Toroslar/Mersin, Mersin 33240, Mersin, Türkiye. ysahin977@gmail.com |
| Key Words |
Celiac disease; Frequency; Genetic; HLA haplotypes; Intestinal biopsy; Siblings |
| Core Tip |
Celiac disease (CD) is a multifactorial disease, but genetic factors play a major role in its etiology. Human leucocyte antigen-DQ2/DQ8 haplotypes are one of the most important predisposing genetic factors. We detected human leucocyte antigen-DQ alleles in 98.2% of celiac patients and 100% in siblings diagnosed with CD. Also, 1 of the 2 siblings was diagnosed with CD 1 year later and the other 4 years later. Siblings of celiac patients should be followed up with clinical findings and human leucocyte antigen analysis and serological examination. We recommend that siblings should be screened for CD even if they are asymptomatic. |
| Publish Date |
2022-07-06 13:21 |
| Citation |
Sahin Y, Mermer S. Frequency of celiac disease and distribution of HLA-DQ2/DQ8 haplotypes among siblings of children with celiac disease. World J Clin Pediatr 2022; 11(4): 351-359 |
| URL |
https://www.wjgnet.com/2219-2808/full/v11/i4/351.htm |
| DOI |
https://dx.doi.org/10.5409/wjcp.v11.i4.351 |
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