Publication Name	World Journal of Stem Cells
Manuscript ID	74928
Country	China

Received	2022-01-11 12:31
Peer-Review Started	2022-01-11 12:33
To Make the First Decision
Return for Revision	2022-03-11 23:48
Revised	2022-03-19 03:41
Second Decision	2022-04-18 02:16
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-04-25 22:17
Articles in Press	2022-04-25 22:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-04-26 10:30
Publish the Manuscript Online	2022-04-26 15:45

ISSN	1948-0210 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Medicine, Research & Experimental
Manuscript Type	Review
Article Title	Correlation between amino acid metabolism and self-renewal of cancer stem cells: Perspectives in cancer therapy
Manuscript Source	Unsolicited Manuscript
All Author List	Qi Zhang and Wei Li
ORCID	Author(s) ORCID Number Qi Zhang http://orcid.org/0000-0001-8992-2295 Wei Li http://orcid.org/0000-0002-9991-7892
Funding Agency and Grant Number	Funding Agency Grant Number Capital’s Funds for Health Improvement and Research (CFH) 2020-2-2175 Beijing Talents Project
Corresponding Author	Wei Li, PhD, Chief Doctor, Professor, Cancer Center, Beijing Ditan Hospital, Capital Medical University, Jingshun East Street, Beijing 100015, China. weili8989@ccmu.edu.cn
Key Words	Amino acid metabolism; Cancer stem cell; Self-renewal; Resistance
Core Tip	Amino acid metabolism plays an important role in maintaining the stemness of cancer stem cells (CSCs) and is involved in regulating their self-renewal and differentiation potential. This review summarizes the relationship between CSCs and amino acid metabolism and discusses possible mechanisms via which amino acid metabolism regulates the self-renewal and differentiation potential of CSCs. The ultimate goal is to identify new targets and research directions for elimination of CSCs.
Publish Date	2022-04-26 15:45
Citation	Zhang Q, Li W. Correlation between amino acid metabolism and self-renewal of cancer stem cells: Perspectives in cancer therapy. World J Stem Cells 2022; 14(4): 267-286
URL	https://www.wjgnet.com/1948-0210/full/v14/i4/267.htm
DOI	https://dx.doi.org/10.4252/wjsc.v14.i4.267

Full Article (PDF)	WJSC-14-267.pdf
Full Article (Word)	WJSC-14-267.docx
Manuscript File	74928_Auto_Edited_LM.docx
Answering Reviewers	74928-Answering reviewers.pdf
Audio Core Tip	74928-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	74928-Conflict-of-interest statement.pdf
Copyright License Agreement	74928-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	74928-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	74928-Language certificate.pdf
Peer-review Report	74928-Peer-review(s).pdf
Scientific Misconduct Check	74928-Bing-Fan JR-2.png
Scientific Editor Work List	74928-Scientific editor work list.pdf
CrossCheck Report	74928-CrossCheck report.pdf
CrossCheck Report	74928-CrossCheck.png