Publication Name	World Journal of Clinical Cases
Manuscript ID	74946
Country	China

Received	2022-01-12 04:36
Peer-Review Started	2022-01-12 04:38
To Make the First Decision
Return for Revision	2022-05-11 09:02
Revised	2022-05-19 07:31
Second Decision	2022-07-01 03:09
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2022-07-06 03:39
Articles in Press	2022-07-06 03:39
Publication Fee Transferred
Edit the Manuscript by Language Editor	2022-06-22 02:28
Typeset the Manuscript	2022-07-08 08:32
Publish the Manuscript Online	2022-07-22 07:03

ISSN	2307-8960 (online)
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Category	Neurosciences
Manuscript Type	Case Report
Article Title	Clinical and genetic analysis of nonketotic hyperglycinemia: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Jun-Jie Ning, Feng Li and Sheng-Qiu Li
ORCID	Author(s) ORCID Number Jun-Jie Ning http://orcid.org/0000-0002-8555-5480 Feng Li http://orcid.org/0000-0002-7611-3322 Sheng-Qiu Li http://orcid.org/0000-0001-5333-9276
Funding Agency and Grant Number
Corresponding Author	Jun-Jie Ning, MD, Attending Doctor, Department of Pediatric Intensive Care Unit, First People's Hospital of Zigong City, No. 42 Shangyi Haozhi Road, Zigong 643000, Sichuan Province, China. 196425984@qq.com
Key Words	Nonketotic hyperglycinemia; Compound heterozygosity; GLDC gene; Case report
Core Tip	Herein, we present the case of a child who had typical clinical manifestations of nonketotic hyperglycinemia (NKH), such as hiccups, disturbance of consciousness, hypotonia and convulsions within the first week after birth. These symptoms combined with the results of gene testing led to a diagnosis of classical nonketotic hyperglycinemia caused by compound heterozygous variants in the GLDC gene. Plasma glycine levels cannot be used to evaluate the prognosis of NKH, and the corpus callosum can be affected by NKH. A ketogenic diet may be effective for seizure control in NKH patients.
Publish Date	2022-07-22 07:03
Citation	Ning JJ, Li F, Li SQ. Clinical and genetic analysis of nonketotic hyperglycinemia: A case report. World J Clin Cases 2022; 10(22): 7982-7988
URL	https://www.wjgnet.com/2307-8960/full/v10/i22/7982.htm
DOI	https://dx.doi.org/10.12998/wjcc.v10.i22.7982

Full Article (PDF)	WJCC-10-7982.pdf
Full Article (Word)	WJCC-10-7982.docx
Manuscript File	74946_Auto_Edited-JRF-Wang TQ-LS.docx
Answering Reviewers	74946-Answering reviewers.pdf
Audio Core Tip	74946-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	74946-Conflict-of-interest statement.pdf
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Signed Consent for Treatment Form(s) or Document(s)	74946-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	74946-Language certificate.pdf
Video	74946-Video.mp4
Peer-review Report	74946-Peer-review(s).pdf
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Scientific Editor Work List	74946-Scientific editor work list.pdf
CrossCheck Report	74946-CrossCheck report.pdf
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