Publication Name	World Journal of Gastrointestinal Endoscopy
Manuscript ID	7496
Country	Norway

Received	2013-11-22 07:53
Peer-Review Started	2013-11-22 20:56
To Make the First Decision	2013-12-25 18:13
Return for Revision	2013-12-27 20:40
Revised	2013-12-31 21:50
Second Decision	2014-02-18 11:53
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-02-18 12:16
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-05-10 22:15
Publish the Manuscript Online	2014-05-20 12:16

ISSN	1948-5190 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Endocrine cells in the oxyntic mucosa of the stomach in patients with irritable bowel syndrome
Manuscript Source	Invited Manuscript
All Author List	Magdy El-Salhy, Odd Helge Gilja, Doris Gundersen and Trygve Hausken
Funding Agency and Grant Number	Funding Agency Grant Number Helse-Fonna, 3072 Haugesund, Norway
Corresponding Author	Magdy El-Salhy, Professor, Consultant Gastroenterologist, Section for Gastroenterology, Department of Medicine, Stord Helse-Fonna Hospital, Box 4000, 5409 Stord, Norway. magdy.el-salhy@helse-fonna.no
Key Words	Birmingham irritable bowel syndrome symptom questionnaire; Ghrelin; Immunohistochemistry; Serotonin; Somatostatin
Core Tip	There are four endocrine cell types in the oxyntic mucosa of the stomach: ghrelin, serotonin, somatostatin and histamine-containing (enterochromaffin-like) cells. These cells regulate several functions that are disturbed in patients with irritable bowel syndrome (IBS), such as motility and visceral sensation. Of all these cell types, ghrelin cells are the only endocrine cell type that has been studied in IBS patients. The present study investigated all the oxyntic mucosa endocrine cell types and reported several abnormalities that can shed light on the pathophysiology of IBS.
Publish Date	2014-05-20 12:16
Citation	El-Salhy M, Gilja OH, Gundersen D, Hausken T. Endocrine cells in the oxyntic mucosa of the stomach in patients with irritable bowel syndrome. World J Gastrointest Endosc 2014; 6(5): 176-185
URL	http://www.wjgnet.com/1948-5190/full/v6/i5/176.htm
DOI	http://dx.doi.org/10.4253/wjge.v6.i5.176

Full Article (PDF)	WJGE-6-176.pdf
Manuscript File	7496-Review.doc
Answering Reviewers	7496-Answering reviews.pdf
Copyright License Agreement	7496-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	7496-Language certificate.pdf
Peer-review Report	7496-Peer review(s).pdf
Scientific Editor Work List	7496-Scientific editor work list.doc