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7/5/2022 1:22:29 AM | Browse: 221 | Download: 602
Publication Name World Journal of Clinical Cases
Manuscript ID 74986
Country Japan
Received
2022-01-13 05:05
Peer-Review Started
2022-01-13 05:05
To Make the First Decision
Return for Revision
2022-03-16 00:25
Revised
2022-03-17 07:56
Second Decision
2022-04-21 02:23
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2022-04-24 05:16
Articles in Press
2022-04-24 05:16
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2022-06-22 01:56
Publish the Manuscript Online
2022-07-05 01:22
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Otorhinolaryngology
Manuscript Type Retrospective Cohort Study
Article Title Effects of Kampo medicine hangebyakujutsutemmato on persistent postural-perceptual dizziness: A retrospective pilot study
Manuscript Source Unsolicited Manuscript
All Author List Toru Miwa and Shin-ichi Kanemaru
ORCID
Author(s) ORCID Number
Toru Miwa http://orcid.org/0000-0002-5977-0056
Shin-ichi Kanemaru http://orcid.org/0000-0001-8424-9345
Funding Agency and Grant Number
Corresponding Author Toru Miwa, MD, PhD, Neurosurgeon, Research Scientist, Department of Otolaryngology-Head and Neck Surgery, Osaka Metropolitan University, 1-4-3 Asahi-cho, Abeno-ku, Osaka 5458585, Japan. miw.com1101@gmail.com
Key Words Hangebyakujutsutemmato; Kampo medicine; Persistent postural-perceptual dizziness; Niigata persistent postural-perceptual dizziness questionnaire score; Sensory reweighting; Treatment responder
Core Tip Persistent postural-perceptual dizziness (PPPD) is characterized by a shift in processing spatial orientation information to favor visual or somatosensory information over vestibular inputs, as well as failure of higher cortical mechanisms. Our retrospective study showed that Kampo medicine Hangebyakujutsutemmato (HBT) was effective as an adjunctive therapy for PPPD. Additionally, HBT responders had baseline autonomic dysfunction, unstable balance, semicircular canal paresis, anxiety, and poor sleep quality. According to our results, and previous reports, several herbal ingredients in HBT might improve autonomic function and the cyclic AMP response element binding protein/the brain-derived neurotrophic factor pathway, resulting in sensory reweighting to establish a balance between the systems involved in PPPD.
Publish Date 2022-07-05 01:22
Citation Miwa T, Kanemaru S. Effects of Kampo medicine hangebyakujutsutemmato on persistent postural-perceptual dizziness: A retrospective pilot study. World J Clin Cases 2022; 10(20): 6811-6824
URL https://www.wjgnet.com/2307-8960/full/v10/i20/6811.htm
DOI https://dx.doi.org/10.12998/wjcc.v10.i20.6811
Full Article (PDF) WJCC-10-6811.pdf
Full Article (Word) WJCC-10-6811.docx
STROBE Statement 74986-STROBE-Statement-revision.pdf
Manuscript File 74986_Auto_Edited_LM.docx
Answering Reviewers 74986-Answering reviewers.pdf
Audio Core Tip 74986-Audio core tip.m4a
Biostatistics Review Certificate 74986-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 74986-Conflict-of-interest statement.pdf
Copyright License Agreement 74986-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 74986-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 74986-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 74986-Language certificate.pdf
Supplementary Material 74986-Supplementary material.pdf
Peer-review Report 74986-Peer-review(s).pdf
Scientific Misconduct Check 74986-Bing-Fan JR-2.png
Scientific Editor Work List 74986-Scientific editor work list.pdf
CrossCheck Report 74986-CrossCheck report.pdf
CrossCheck Report 74986-CrossCheck.png