Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	7502
Country	Italy

Received	2013-11-22 08:23
Peer-Review Started	2013-11-22 20:17
To Make the First Decision	2013-12-25 18:13
Return for Revision	2013-12-27 20:32
Revised	2014-01-10 21:06
Second Decision	2014-02-18 11:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-02-18 12:18
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-03-12 20:54
Publish the Manuscript Online	2014-03-20 18:58

ISSN	1948-5204 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Xenoestrogens challenge 17β-estradiol protective effects in colon cancer
Manuscript Source	Invited Manuscript
All Author List	Maria Marino
Funding Agency and Grant Number	Funding Agency Grant Number University Roma Tre
Corresponding Author	Maria Marino, PhD, Professor, Department of Science, University Roma Tre, Viale G. Marconi 446, I-00146 Roma, Italy. maria.marino@uniroma3.it
Key Words	17β-Estradiol; Estrogen receptors; Xenoestrogens; Bisphenol A; Flavonoids; Colorectal cancer
Core Tip	In this review, we will report recent data, including ours, on 17?-estradiol (E2) action in colon health and disease discussing on how environmental chemicals with endocrine disrupting activities could impact on these E2 effects in colon cancer. In particular, two plant-derived flavonoids (i.e., naringenin, Nar, and quercetin, Que) and one synthetic food-contaminant bisphenol A will be reported as prototype molecules to evaluate how xenoestrogens can impact on cell proliferation/apoptosis balance, the critical physiological function of E2 in colon.
Publish Date	2014-03-20 18:58
Citation	Marino M. Xenoestrogens challenge 17β-estradiol protective effects in colon cancer. World J Gastrointest Oncol 2014; 6(3): 67-73
URL	http://www.wjgnet.com/1948-5204/full/v6/i3/67.htm
DOI	http://dx.doi.org/10.4251/wjgo.v6.i3.67

Full Article (PDF)	wjgo-6-67.pdf
Full Article (Word)	wjgo-6-67.doc
Manuscript File	7502-Review.doc
Answering Reviewers	7502-Answering reviews.pdf
Copyright License Agreement	7502-Copyright Assignment.pdf
Non-Native Speakers of English Editing Certificate	7502-Language certificate.pdf
Peer-review Report	7502-Peer review(s).pdf
Scientific Editor Work List	7502-Scientific editor work list.doc