Publication Name	World Journal of Gastroenterology
Manuscript ID	75051
Country	United States

Received	2022-01-21 17:35
Peer-Review Started	2022-01-21 17:37
To Make the First Decision
Return for Revision	2022-02-24 07:00
Revised	2022-02-28 19:42
Second Decision	2022-03-22 06:32
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2022-03-27 05:22
Articles in Press	2022-03-27 05:22
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2022-04-01 14:16
Publish the Manuscript Online	2022-04-29 06:42

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Letter to the Editor
Article Title	Could microbiome analysis be a new diagnostic tool in gastric carcinogenesis for high risk, Helicobacter pylori negative patients?
Manuscript Source	Invited Manuscript
All Author List	Alla Turshudzhyan and Houman Rezaizadeh
ORCID	Author(s) ORCID Number Alla Turshudzhyan http://orcid.org/0000-0001-6867-7569 Houman Rezaizadeh http://orcid.org/0000-0002-1066-5394
Funding Agency and Grant Number
Corresponding Author	Houman Rezaizadeh, MD, Assistant Professor, Department of Gastroenterology and Hepatology, University of Connecticut, 263 Farmington Ave, Farmington, CT 06030, United States. rezaizadeh@uchc.edu
Key Words	Gastric cancer; Gastric carcinogenesis; Microbiome; Dysplasia; Intestinal metaplasia
Core Tip	Gastric tumorigenesis in Helicobacter pylori (H. pylori) negative patients remained a mystery for many years until genetic sequencing allowed for a closer look at the composition of the gastric microbiome. Primary colonizers of the stomach in H. pylori negative patients at various stages of gastric tumorigenesis and were able to conclude that there are distinct bacterial taxa associated with these stages. Their study is comprehensive but needs a larger prospective study to further support this hypothesis, particularly in other geographic areas with varying risk profiles.
Publish Date	2022-04-29 06:42
Citation	Turshudzhyan A, Rezaizadeh H. Could microbiome analysis be a new diagnostic tool in gastric carcinogenesis for high risk, Helicobacter pylori negative patients? World J Gastroenterol 2022; 28(17): 1871-1874
URL	https://www.wjgnet.com/1007-9327/full/v28/i17/1871.htm
DOI	https://dx.doi.org/10.3748/wjg.v28.i17.1871

Full Article (PDF)	WJG-28-1871.pdf
Full Article (Word)	WJG-28-1871.docx
Manuscript File	75051_Auto_Edited.docx
Answering Reviewers	75051-Answering reviewers.pdf
Audio Core Tip	75051-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	75051-Conflict-of-interest statement.pdf
Copyright License Agreement	75051-Copyright license agreement.pdf
Peer-review Report	75051-Peer-review(s).pdf
Scientific Misconduct Check	75051-Bing-Fan JR-2.png
Scientific Editor Work List	75051-Scientific editor work list.pdf