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Articles Published Processes
7/4/2022 12:30:52 PM | Browse: 389 | Download: 678
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Received |
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2022-01-15 10:55 |
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Peer-Review Started |
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2022-01-15 10:56 |
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To Make the First Decision |
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Return for Revision |
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2022-03-08 19:34 |
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Revised |
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2022-03-22 09:26 |
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Second Decision |
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2022-05-26 02:25 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-05-28 03:27 |
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Articles in Press |
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2022-05-28 03:27 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2022-05-22 02:08 |
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Typeset the Manuscript |
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2022-06-22 03:36 |
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Publish the Manuscript Online |
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2022-07-04 12:30 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Minireviews |
| Article Title |
Micelles as potential drug delivery systems for colorectal cancer treatment
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Zaynab Fatfat, Maamoun Fatfat and Hala Gali-Muhtasib |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Hala Gali-Muhtasib, PhD, Professor, Department of Biology, American University of Beirut, Bliss Street, Beirut 1107 2020, Lebanon. amro@aub.edu.lb |
| Key Words |
Polymeric micelles; Drug delivery; Colorectal cancer; Chemotherapy; Gene therapy; Combination cancer therapy |
| Core Tip |
Polymeric micelle-based drug delivery has demonstrated promising therapeutic outcomes against colorectal cancer. These safe nanocarriers exhibit high encapsulation efficiency of chemotherapeutic drugs, improve their water solubility and enhance the stability of nucleic acid-based therapeutics. They also accumulate preferentially at colorectal cancer sites, increase the anticancer effect of the delivered therapeutics and reduce their side effects. Incorporating stimuli-responsive and tumor targeting moieties to their structure further enhances their targeting and therapeutic efficacy. This platform also provides an opportunity to simultaneously deliver different chemotherapeutic drugs or nucleic acid-based therapeutics with chemotherapeutic drugs to the colorectal tumor to achieve an enhanced anticancer response. |
| Publish Date |
2022-07-04 12:30 |
| Citation |
Fatfat Z, Fatfat M, Gali-Muhtasib H. Micelles as potential drug delivery systems for colorectal cancer treatment. World J Gastroenterol 2022; 28(25): 2867-2880 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i25/2867.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i25.2867 |
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