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Articles Published Processes
7/18/2022 9:47:46 AM | Browse: 492 | Download: 989
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Received |
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2022-01-16 20:49 |
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Peer-Review Started |
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2022-01-16 20:50 |
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To Make the First Decision |
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Return for Revision |
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2022-04-11 08:47 |
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Revised |
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2022-04-22 15:21 |
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Second Decision |
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2022-06-13 03:14 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-06-20 15:46 |
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Articles in Press |
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2022-06-20 15:46 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-06-23 09:09 |
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Publish the Manuscript Online |
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2022-07-18 09:47 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Tumor microenvironment in pancreatic ductal adenocarcinoma: Implications in immunotherapy
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Caitlyn Smith, Wei Zheng, Jixin Dong, Yaohong Wang, Jinping Lai, Xiuli Liu and Feng Yin |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Feng Yin, MD, PhD, Assistant Professor, Department of Pathology and Anatomical Sciences, University of Missouri, One Hospital Drive, MSB M263, Columbia, MO 65212, United States. fengyin@health.missouri.edu |
| Key Words |
Pancreatic ductal adenocarcinoma; Tumor microenvironment; Immunotherapy; Clinical trial; Chemotherapy; Treatment |
| Core Tip |
Despite advances in basic and translational research, pancreatic cancer remains one of the most lethal cancers. Recent breakthroughs in immunotherapy have revolutionized cancer therapy and have shown great potential to transform pancreatic cancer treatment. However, due to the barrier related to the tumor microenvironment, pancreatic cancer has shown inferior treatment outcomes toward various immunotherapy regimens. Further efforts, such as combinatory immunotherapy or molecular tumor subtyping, are warranted to overcome immunotherapy resistance in pancreatic cancer. |
| Publish Date |
2022-07-18 09:47 |
| Citation |
Smith C, Zheng W, Dong J, Wang Y, Lai J, Liu X, Yin F. Tumor microenvironment in pancreatic ductal adenocarcinoma: Implications in immunotherapy. World J Gastroenterol 2022; 28(27): 3297-3313 |
| URL |
https://www.wjgnet.com/1007-9327/full/v28/i27/3297.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v28.i27.3297 |
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